Evidence map›Paper›PMID 28074077›Full record

SynthesisDisease markers2016

Identification of Gingival Crevicular Fluid Sampling, Analytical Methods, and Oral Biomarkers for the Diagnosis and Monitoring of Periodontal Diseases: A Systematic Review.

Zeyad Nazar Majeed, Koshy Philip, A M Alabsi, Saravanan Pushparajan, Dasan Swaminathan

Registry-linked trialOpen access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Disease markers, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03522532 (Redox Interactions Between Dental Restorations and Gingival Crevicular Fluid), which is not on this map. Cited by 50 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03522532 nacompletednot on this map

Redox Interactions Between Dental Restorations and Gingival Crevicular Fluid

TypeinterventionalSponsorErvin TasoRan2016 to 2017Enrolled88ConditionsPharmacological ActionArmsAmalgam placement, Tetric EvoCeram placement, Beautifil placement, Zinc phosphate cement placement, Zinc polycarboxylate cement placement
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Periodontal disease metabolomics signatures from different biofluids: a systematic review.Metabolomics : Official journal of the Metabolomic Society · 2022
    Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Prevalence ofPathogens (Basel, Switzerland) · 2026
    Observational
  8. Article
  9. Article
  10. SmartGel OV: A NaturalMedicina (Kaunas, Lithuania) · 2025
    Observational
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. A GMR enzymatic assay for quantifying nuclease and peptidase activity.Frontiers in bioengineering and biotechnology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Zeyad Nazar MajeedDepartment of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia; Department of Periodontology, Faculty of Dentistry, University of Babylon, Babylon, Iraq.
Koshy PhilipInstitute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0001-8392-6383
A M AlabsiDepartment of Oral and Craniofacial Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0001-8981-7567
Saravanan PushparajanDepartment of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
Dasan SwaminathanDepartment of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0002-7418-9796
University of Malaya · MYUniversity of Babylon · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkersGingival Crevicular FluidHumansInterleukin-1betaMatrix Metalloproteinase 8Periodontal DiseasesSpecimen HandlingTumor Necrosis Factor-alphaBiomarkersInterleukin-1betaMatrix Metalloproteinase 8MMP8 protein, humanTumor Necrosis Factor-alpha

Identifiers

PMID28074077
PMCPMC5198140
OpenAlexW2567377008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.