Evidence map›Paper›PMID 28074049›Full record

ArticleThe Journal of antibiotics2017

In vitro antibacterial activity of α-methoxyimino acylide derivatives against macrolide-resistant pathogens and mutation analysis in 23S rRNA.

Hiroyuki Sugiyama, Ippei Yoshida, Mayumi Ueki, Katsuhiko Tanabe, Akira Manaka, Keiichi Hiramatsu

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in The Journal of antibiotics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hiroyuki SugiyamaPharmacology Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
Ippei YoshidaPharmacology Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
Mayumi UekiPharmacology Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
Katsuhiko TanabePharmacology Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
Akira ManakaPharmaceutical Science Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
Keiichi HiramatsuDepartment of Infection Control Science, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Taisho Pharmaceutical (Japan) · JPJuntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We characterized in vitro activities of α-methoxyimino acylides against macrolide-resistant clinical isolates of Streptococcus pneumoniae, Streptococcus pyogenes and Mycoplasma pneumoniae with ribosome modification or substitution and selected acylide-resistant mutants to clarify the binding point of the acylides. The acylides had low MICs against erm(B) gene-containing S. pneumoniae and S. pyogenes (MIC

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialMacrolidesMicrobial Sensitivity TestsModels, MolecularMutationMycoplasma pneumoniaeRNA, Ribosomal, 23SStreptococcus pneumoniaeStreptococcus pyogenesAnti-Bacterial AgentsMacrolidesRNA, Ribosomal, 23S

Identifiers

PMID28074049
OpenAlexW2575243699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.