Evidence map›Paper›PMID 28073911›Full record

ArticleThe Journal of biological chemistry2017

A Truncated Granulocyte Colony-stimulating Factor Receptor (G-CSFR) Inhibits Apoptosis Induced by Neutrophil Elastase G185R Mutant: IMPLICATION FOR UNDERSTANDING CSF3R GENE MUTATIONS IN SEVERE CONGENITAL NEUTROPENIA.

Yaling Qiu, Yangyang Zhang, Nan Hu, Fan Dong

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Inducible expression of a disease-associatedThe Journal of biological chemistry · 2020
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yaling QiuDepartment of Biological Sciences, University of Toledo, Toledo, Ohio 43606.
Yangyang ZhangDepartment of Biological Sciences, University of Toledo, Toledo, Ohio 43606.
Nan HuDepartment of Biological Sciences, University of Toledo, Toledo, Ohio 43606.
Fan DongDepartment of Biological Sciences, University of Toledo, Toledo, Ohio 43606. Electronic address: fan.dong@utoledo.edu.
University of Toledo · US

Funding

ELANE and CSF3R mutations in severe congenital neutropeniaR15HL112183 · NHLBI · UNIVERSITY OF TOLEDO · PI DONG, FAN · 2012 to 2012
$437k
NHLBI NIH HHS R15 HL112183
6 · The paper itself

Abstract

Mutations in

Indexed as

ApoptosisMutationAnimalsCell DifferentiationCell LineCongenital Bone Marrow Failure SyndromesHumansLeukemia, Myeloid, AcuteLeukocyte ElastaseMiceNeutropeniaPoint MutationReceptors, Colony-Stimulating FactorUnfolded Protein ResponseCSF3R protein, humanLeukocyte ElastaseReceptors, Colony-Stimulating Factorapoptosiscell differentiationcell surface receptorleukemianeutrophil

Identifiers

PMID28073911
PMCPMC5336180
OpenAlexW2571092465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.