Evidence map›Paper›PMID 28073873›Full record

ArticleBMJ case reports2017

Recurrent angioedema associated with pharmacological inhibition of dipeptidyl peptidase IV.

Thorbjørn Hermanrud, Anette Bygum, Eva Rye Rasmussen

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Bradykinin-Mediated Angioedema Induced by Drugs.Journal of clinical medicine · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Angioedema associated with dipeptidyl peptidase-IV inhibitors.Clinical and molecular allergy : CMA · 2021
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Thorbjørn HermanrudDepartment of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen, Denmark.
Anette BygumDermatology and Allergy Center, University Hospital of Odense, Odense, Denmark.
Eva Rye RasmussenDepartment of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen, Denmark.
Rigshospitalet · DKOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angioedema (AE) of the upper airways is a severe and potentially life-threatening condition. The incidence has been increasing in the past two decades, primarily due to increased use of medications inhibiting the degradation of vasoactive peptides. Acquired angioedema related to angiotensin-converting enzyme inhibitors (ACEI-AAE) is well known, but other pharmaceutical agents also affect the degradation of bradykinin and substance P. We present a middle-aged man with recurrent episodes of severe AE of the oral cavity, hypopharynx and larynx due to pharmacological inhibition of dipeptidyl peptidase IV.

Indexed as

AngioedemaAngiotensin-Converting Enzyme InhibitorsDiagnosis, DifferentialDipeptidyl-Peptidase IV InhibitorsDrug InteractionsHumansHypopharynxLaryngeal EdemaMaleMiddle AgedMouth DiseasesPharyngeal DiseasesAngiotensin-Converting Enzyme InhibitorsDipeptidyl-Peptidase IV Inhibitors

Identifiers

PMID28073873
PMCPMC5256585
OpenAlexW2569069590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.