Evidence map›Paper›PMID 28073857›Full record

ArticleThe Journal of infectious diseases2017

First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease.

Jenny Dörnemann, Chiara Burzio, Axelle Ronsse, Armand Sprecher, Hilde De Clerck, Michel Van Herp, Marie-Claire Kolié, Vesselina Yosifiva, Severine Caluwaerts, Anita K McElroy and 1 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in The Journal of infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 4 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 4 syntheses or guidelines pooled it, 127 citations in OpenAlex.

  1. Pooled it
  2. Ebola virus disease in pregnancy: a systematic review and meta-analysis.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Observational
  13. Review
  14. Protecting Breastfeeding during the COVID-19 Pandemic.American journal of perinatology · 2023
    Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Jenny DörnemannMédecins Sans Frontières, Brussels.
Chiara BurzioMédecins Sans Frontières, Brussels.
Axelle RonsseMédecins Sans Frontières, Brussels.
Armand SprecherMédecins Sans Frontières, Brussels.
Hilde De ClerckMédecins Sans Frontières, Brussels.
Michel Van HerpMédecins Sans Frontières, Brussels.
Marie-Claire KoliéMédecins Sans Frontières, Conakry, Guinea.
Vesselina YosifivaMédecins Sans Frontières, Brussels.
Severine CaluwaertsMédecins Sans Frontières, Brussels.
Anita K McElroyCenters for Disease Control and Prevention.
Annick AntierensMédecins Sans Frontières, Brussels.
Médecins Sans Frontières · BEGamal Abdel Nasser University of Conakry · GN

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

A neonate born to an Ebola virus-positive woman was diagnosed with Ebola virus infection on her first day of life. The patient was treated with monoclonal antibodies (ZMapp), a buffy coat transfusion from an Ebola survivor, and the broad-spectrum antiviral GS-5734. On day 20, a venous blood specimen tested negative for Ebola virus by quantitative reverse-transcription polymerase chain reaction. The patient was discharged in good health on day 33 of life. Further follow-up consultations showed age-appropriate weight gain and neurodevelopment at the age of 12 months. This patient is the first neonate documented to have survived congenital infection with Ebola virus.

Indexed as

Adenosine MonophosphateAlanineAntibodies, MonoclonalAntiviral AgentsBloodFemaleHemorrhagic Fever, EbolaHumansImmunologic FactorsInfant, NewbornPregnancyRibonucleotidesTherapies, InvestigationalTreatment OutcomeYoung AdultAdenosine MonophosphateAlanineAntibodies, MonoclonalAntiviral AgentsImmunologic FactorsremdesivirRibonucleotidesZMappEbolaGS-5734ZMapp

Identifiers

PMID28073857
PMCPMC5583641
OpenAlexW2571461673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.