ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017
Active Estrogen Receptor-alpha Signaling in Ovarian Cancer Models and Clinical Specimens.
Abstract read
In one paragraph
Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
9.1field-weighted citation impact, top 2% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Impact of estrogen receptor expression on prognosis of ovarian cancer according to antibody clone used for immunohistochemistry: a meta-analysis.Journal of ovarian research · 2022Pooled it
- Phase II trial of ribociclib and letrozole in patients with relapsed oestrogen receptor-positive ovarian or endometrial cancers.ESMO open · 2020Trial
- CRISPR activation screens identify oncogenic lncRNAs that are susceptible to CDK4/6 inhibitor treatment.Nature communications · 2026Article
- When Estrogen Signaling Refuses to Die: Receptor Rewiring, Compartmentalization, and Endocrine Plasticity in Gynecological Cancers.International journal of molecular sciences · 2026Review
- Mutant p53 binds and controls estrogen receptor activity to drive endocrine resistance in ovarian cancer.Genes & development · 2026Article
- Divergent ERα co-factor landscapes in gynecological cancers: implications for disease progression and therapy.Biochemistry and cell biology = Biochimie et biologie cellulaire · 2025Review
- S-Dihydrodaidzein and 3-(1,3-benzoxazol-2-yl)-benzamide, Two New Potential β-estrogen Receptor Ligands with Anti-adipogenic Activity.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2024Article
- Current Understanding on Why Ovarian Cancer Is Resistant to Immune Checkpoint Inhibitors.International journal of molecular sciences · 2023Review
- Identification of an Autophagy-Related Signature for Prognosis and Immunotherapy Response Prediction in Ovarian Cancer.Biomolecules · 2023Article
- The m6A-Related Long Noncoding RNA Signature Predicts Prognosis and Indicates Tumor Immune Infiltration in Ovarian Cancer.Cancers · 2022Article
- microRNA-26b inhibits growth and cellular invasion of ovarian cancer cells by targeting estrogen receptor α.3 Biotech · 2022Article
- Article
- Hormone therapy for ovarian cancer: Emphasis on mechanisms and applications (Review).Oncology reports · 2021Review
- Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer.BMC cancer · 2021Article
- Expression of hormone receptors predicts survival and platinum sensitivity of high-grade serous ovarian cancer.Bioscience reports · 2021Article
- The Cell-Free Expression of MiR200 Family Members Correlates with Estrogen Sensitivity in Human Epithelial Ovarian Cells.International journal of molecular sciences · 2020Article
- Aromatase inhibitor use, side effects and discontinuation rates in gynecologic oncology patients.Gynecologic oncology · 2020Article
- Identification of ovarian high-grade serous carcinoma cell lines that show estrogen-sensitive growth as xenografts in immunocompromised mice.Scientific reports · 2020Article
- Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 7 institutions in 1 country.
Courtney L AndersenDepartment of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Matthew J SikoraDepartment of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Michelle M BoisenWomen's Cancer Research Center, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.
Tianzhou MaDepartment of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Alec ChristieWomen's Cancer Research Center, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.
George TsengDepartment of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Yongseok ParkDepartment of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Soumya LuthraDepartment of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Uma ChandranDepartment of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Paul HaluskaOncology, Merck Research Laboratories, Rahway, New Jersey.
Gina M Mantia-SmaldoneDepartment of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Kunle OdunsiDepartment of Gynecologic Oncology, Roswell Park Cancer Institute, New York, New York.
Karen McLeanDivision of Gynecologic Oncology, University of Michigan, Ann Arbor, Michigan.
Adrian V LeeDepartment of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Esther ElishaevDepartment of Pathology, Magee-Womens Hospital of UPMC, Pittsburgh, Pennsylvania.
Robert P EdwardsDepartment of Obstetrics, Gynecology, & Reproductive Sciences, Magee-Womens Hospital of UPMC, Pittsburgh, Pennsylvania.
Steffi OesterreichDepartment of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania. oesterreichs@upmc.edu.
University of Pittsburgh · USMagee-Womens Hospital · USFox Chase Cancer Center · USGynecologic Oncology Group · USMerck & Co., Inc., Rahway, NJ, USA (United States) · USUniversity of Michigan · USUPMC Hillman Cancer Center · US
Funding
VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHN C. BYRD · 1988 to 2026
$158.0MWORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Dietmar J Kappes · 1985 to 2026
$138.8MUse of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancerP50CA136393 · NCI · MAYO CLINIC ROCHESTER · PI ELLEN L. GOODE · 2009 to 2026
$37.0MRPCI-UPCI Ovarian Cancer SPOREP50CA159981 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MOYSICH, KIRSTEN B., ODUNSI, KUNLE · 2013 to 2025
$19.6MPREDOCTORAL TRAINING IN PHARMACOLOGICAL SCIENCEST32GM008424 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PAGANO, PATRICK J · 1994 to 2019
$3.4M(PQD5) Avatar-directed Treatment for Ovarian CancerR01CA184502 · NCI · MAYO CLINIC ROCHESTER · PI WEROHA, SARAVUT · 2014 to 2017
$2.7MElucidating the function of WNT4 in endocrine response and resistance in invasive lobular carcinomaK99CA193734 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SIKORA, MATTHEW J · 2015 to 2016
$256kRole of estrogen receptor-alpha in ovarian cancerF31CA186376 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ANDERSEN, COURTNEY L · 2015 to 2016
$52kNCI NIH HHS F31 CA186376NCI NIH HHS K99 CA193734NCI NIH HHS P30 CA006927NCI NIH HHS P30 CA047904NCI NIH HHS P50 CA136393NCI NIH HHS P50 CA159981NCI NIH HHS R01 CA184502NIGMS NIH HHS T32 GM008424
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsCell Line, TumorCell ProliferationDrug Resistance, NeoplasmEstradiolEstrogen Receptor alphaEstrogensFemaleFulvestrantGene Expression Regulation, NeoplasticHumansInsulin-Like Growth Factor Binding Protein 3MCF-7 CellsMiceOvarian NeoplasmsXenograft Model Antitumor AssaysESR1 protein, humanEstradiolEstrogen Receptor alphaEstrogensFulvestrantIGFBP3 protein, humanInsulin-Like Growth Factor Binding Protein 3
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.