ReviewEvidence-based mental health2017
Cognitive-behavioural therapy for non-motor symptoms of Parkinson's disease: a clinical review.
Review in Evidence-based mental health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Efficacy of non-pharmacological interventions for sleep quality in Parkinson's disease: a systematic review and network meta-analysis.Frontiers in neuroscience · 2024Pooled it
- Cognitive-behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis.Health technology assessment (Winchester, England) · 2021Pooled it
- Efficacy of Cognitive Behavioral Therapy on Mood Disorders, Sleep, Fatigue, and Quality of Life in Parkinson's Disease: A Systematic Review and Meta-Analysis.Frontiers in psychiatry · 2021Pooled it
- Acceptability and Feasibility of a Mindfulness Intervention Delivered via Videoconferencing for People With Parkinson's.Journal of geriatric psychiatry and neurology · 2022Trial
- Cognitive Behavioral Therapy for Anxiety in Parkinson's Disease: A Randomized Controlled Trial.Movement disorders : official journal of the Movement Disorder Society · 2021Trial
- Telephone-based cognitive behavioral therapy for depression in Parkinson disease: A randomized controlled trial.Neurology · 2020Trial
- Sensory focused exercise improves anxiety in Parkinson's disease: A randomized controlled trial.PloS one · 2020Trial
- Non-pharmacological and non-surgical therapies in advanced Parkinson's disease: a narrative review and call to action.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Review
- A Cognitive-Behavioral Model of Apathy in Parkinson's Disease.Parkinson's disease · 2024Article
- Pharmacological and Non-Pharmacological Treatments for Depression in Parkinson's Disease: An Updated Review.Medicina (Kaunas, Lithuania) · 2023Review
- Both Motor and Non-Motor Fluctuations Matter in the Clinical Management of Patients with Parkinson's Disease: An Exploratory Study.Journal of personalized medicine · 2023Article
- Telehealth Transdiagnostic Cognitive Behavioral Therapy for Depression in Parkinson's Disease: A Pilot Randomized Controlled Trial.Movement disorders clinical practice · 2023Article
- Mechanism of Tianma Gouteng Decoction in the treatment of Parkinson's disease based on network pharmacology and molecular docking.American journal of translational research · 2023Article
- Strategies for Behavioral Research in Neurology: Lessons Learned During the COVID-19 Pandemic and Applications for the Future.Current neurology and neuroscience reports · 2021Review
- The Relationship Between Anxiety Disorders and Parkinson's Disease: Clinical and Therapeutic Issues.Current psychiatry reports · 2021Review
- The Relationship Between Autonomic Dysfunction of the Gastrointestinal Tract and Emotional Distress in Patients With Systemic Sclerosis.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2021Article
- A new postural stability-indicator to predict the level of fear of falling in Parkinson's disease patients.Biomedical engineering online · 2020Article
- Internet-based cognitive behavioural therapy programme as an intervention for people diagnosed with adult-onset, focal, isolated, idiopathic cervical dystonia: a feasibility study protocol.Pilot and feasibility studies · 2020Article
- Prioritising target non-pharmacological interventions for research in Parkinson's disease: achieving consensus from key stakeholders.Research involvement and engagement · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuropsychiatric symptoms are common in Parkinson's disease (PD) and have a disproportionate impact on quality of life and carer burden. Pharmacological treatment is the main approach in dealing with these symptoms, but it is limited by variable efficacy and risk of drug interactions. Non-pharmacological approaches using the cognitive-behavioural therapy (CBT) model are viable alternatives and in this review paper we summarise the evidence of CBT for three of the most common psychiatric manifestations of PD: depression and anxiety, impulse-control disorders and insomnia. Most studies modified the usual CBT format to include modules accounting for problems specific to PD: activity scheduling around motoric function, motor symptoms as triggers of anxiety, fear of falling and preparation for disease progression as well as accommodation of materials for suspected executive dysfunction. We found a growing evidence base that CBT (modified to account for PD-specific problems) is effective in the treatment of PD psychiatric symptoms. Where controlled study design was used, moderate effect sizes are reported for the efficacy of CBT for depression, including with distance administration of CBT. The effects were sustained during follow-up which was between 1 and 6 months. In addition, there are some initial data on the effects of CBT on impulse-control disorders and insomnia. The studies were limited by their small and potentially unrepresentative samples and the quality of sample reporting (eg, concomitant antidepressant and dopaminergic therapy use). Additional well-designed and adequately powered studies are required to determine the utility of CBT in PD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.