Evidence map›Paper›PMID 28073358›Full record

Observational studyBMC medical informatics and decision making2017

Applying openEHR's Guideline Definition Language to the SITS international stroke treatment registry: a European retrospective observational study.

Nadim Anani, Michael V Mazya, Rong Chen, Tiago Prazeres Moreira, Olivier Bill, Niaz Ahmed, Nils Wahlgren, Sabine Koch

Abstract readObservational Study
In one paragraph

Observational study in BMC medical informatics and decision making, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. What Role Can Process Mining Play in Recurrent Clinical Guidelines Issues? A Position Paper.International journal of environmental research and public health · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nadim AnaniHealth Informatics Centre, LIME, Karolinska Institutet, Tomtebodavägen 18, Stockholm, SE 17177, Sweden. nanani@gmx.de.ORCID 0000-0003-2975-4589
Michael V MazyaDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Rong ChenHealth Informatics Centre, LIME, Karolinska Institutet, Tomtebodavägen 18, Stockholm, SE 17177, Sweden.
Tiago Prazeres MoreiraDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Olivier BillDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Niaz AhmedDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Nils WahlgrenDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Sabine KochHealth Informatics Centre, LIME, Karolinska Institutet, Tomtebodavägen 18, Stockholm, SE 17177, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInteroperability standards intend to standardise health information, clinical practice guidelines intend to standardise care procedures, and patient data registries are vital for monitoring quality of care and for clinical research. This study combines all three: it uses interoperability specifications to model guideline knowledge and applies the result to registry data.

methodsWe applied the openEHR Guideline Definition Language (GDL) to data from 18,400 European patients in the Safe Implementation of Treatments in Stroke (SITS) registry to retrospectively check their compliance with European recommendations for acute stroke treatment.

resultsComparing compliance rates obtained with GDL to those obtained by conventional statistical data analysis yielded a complete match, suggesting that GDL technology is reliable for guideline compliance checking.

conclusionsThe successful application of a standard guideline formalism to a large patient registry dataset is an important step toward widespread implementation of computer-interpretable guidelines in clinical practice and registry-based research. Application of the methodology gave important results on the evolution of stroke care in Europe, important both for quality of care monitoring and clinical research.

Indexed as

Practice Guidelines as TopicElectronic Health RecordsEuropeGuideline AdherenceHumansRegistriesRetrospective StudiesStrokeGuideline adherenceKnowledge managementPractice guidelinesRegistriesStandards

Identifiers

PMID28073358
PMCPMC5223429

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.