ArticleThe Korean journal of internal medicine2018
Clinical phenotypes of Korean patients with Behcet disease according to gender, age at onset, and HLA-B51.
Article in The Korean journal of internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Behçet's Disease: A Comprehensive Review on the Role ofInternational journal of molecular sciences · 2023Pooled it
- Risk of intestinal involvement in mucocutaneous-onset Behçet's disease: data from the AIDA network registry.Frontiers in immunology · 2026Article
- Vascular Involvement in Behçet's Disease: A Retrospective Analysis of Qatar Behçet's Cohort.Open access rheumatology : research and reviews · 2026Article
- HLA-B5 prevalence in patients with spondyloarthritis and impact on disease phenotype: a multicentric case-control study.Rheumatology (Oxford, England) · 2025Observational
- Reclassification of the overlap syndrome of Behçet's disease and antineutrophil cytoplasmic antibody-associated vasculitis in patients with Behçet's disease.The Korean journal of internal medicine · 2025Article
- Assessing disease phenotypes in Behçet's syndrome: insights from a multiple correspondence analysis.Frontiers in immunology · 2025Article
- Epidemiologic and Etiological Features of Korean Patients With Behçet's Disease.Journal of rheumatic diseases · 2021Review
- Characteristics and phenotype heterogeneity in late-onset Behçet's syndrome: a cohort from a referral center in China.Clinical rheumatology · 2021Article
- Male Sex Is a Significant Predictor of All-cause Mortality in Patients with Antineutrophil Cytoplasmic Antibody-associated Vasculitis.Journal of Korean medical science · 2021Article
- Cluster analysis of phenotypes of patients with Behçet's syndrome: a large cohort study from a referral center in China.Arthritis research & therapy · 2021Article
- Past and Present Behçet's Disease Animal Models.Current drug targets · 2020Review
- Behçet's disease in Egypt: a multicenter nationwide study on 1526 adult patients and review of the literature.Clinical rheumatology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND/
aimsThe clinical manifestations of Behcet disease (BD) have been reported to differ according to country, region, and race. Gender, onset age, and human leukocyte antigen (HLA)-B51 have also been known as the factors that influence the clinical features of BD. The aim of this study is to investigate the clinical phenotypes of Korean patients who visited the rheumatology clinic with BD with respect to gender, onset age, and HLA-B51.
methodsTotal 193 Korean patients (129 females and 64 males) fulfilling the international criteria for BD were retrospectively assessed.
resultsThe mean age at disease onset and disease duration of the BD patients were 32.2 ± 11.1 and 14.2 ± 9.3 years, retrospectively. Females suffered more frequently from genital ulcers (90.7% vs. 75.0%, p < 0.01), peripheral arthritis (67.4% vs. 43.8%, p < 0.01), and inf lammatory low back pain (38.8% vs. 23.4%, p = 0.03) than males, while skin involvement was more frequent in males than in females (90.6% vs. 75.2%, p = 0.01). The patients with late onset of BD (> 40 years) suffered from neurologic involvement (15.9% vs. 4.2%, p = 0.007) more frequently than those with early onset of BD. The patients with HLA-B51 showed earlier onset of disease than without HLA-B51 (28.3 ± 11.4 years vs. 33.8±11.6 years, p = 0.02) and the neurologic and gastrointestinal involvements were more frequent in the patients without HLA-B51 than with HLA-B51 (17.2% vs. 2.5%, p = 0.02 and 20.7% vs. 2.5%, p = 0.01, respectively).
conclusionThe clinical phenotypes in Korean patients with BD may be influenced by gender, onset age and HLA-B51.
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