ArticlePloS one2017
Identification of the Molecular Clockwork of the Oyster Crassostrea gigas.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- The phenology of the European flat oyster (Ostrea edulis) and its environmental drivers.Scientific reports · 2026Article
- The genome of a keystone predator: adaptive innovations in Charonia tritonis drive specialized predation and coral reef resilience.DNA research : an international journal for rapid publication of reports on genes and genomes · 2026Article
- Coevolution ofiScience · 2025Article
- Article
- Rhythms during the polar night: evidence of clock-gene oscillations in the Arctic scallopProceedings. Biological sciences · 2020Article
- The Still Dark Side of the Moon: Molecular Mechanisms of Lunar-Controlled Rhythms and Clocks.Journal of molecular biology · 2020Review
- Bivalve mollusc circadian clock genes can run at tidal frequency.Proceedings. Biological sciences · 2020Article
- From the raw bar to the bench: Bivalves as models for human health.Developmental and comparative immunology · 2019Review
- Moonlight cycles synchronize oyster behaviour.Biology letters · 2019Article
- Differential Impacts of the Head onFrontiers in physiology · 2019Article
- Sequences of Circadian Clock Proteins in the Nudibranch Molluscs Hermissenda crassicornis, Melibe leonina, and Tritonia diomedea.The Biological bulletin · 2018Article
- Transcriptomic responses of Biomphalaria pfeifferi to Schistosoma mansoni: Investigation of a neglected African snail that supports more S. mansoni transmission than any other snail species.PLoS neglected tropical diseases · 2017Article
- Trojan Horse Strategy for Non-invasive Interference of Clock Gene in the Oyster Crassostrea gigas.Marine biotechnology (New York, N.Y.) · 2017Article
- Remodeling of the cycling transcriptome of the oyster Crassostrea gigas by the harmful algae Alexandrium minutum.Scientific reports · 2017Article
- How annual course of photoperiod shapes seasonal behavior of diploid and triploid oysters, Crassostrea gigas.PloS one · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular clock system constitutes the origin of biological rhythms that allow organisms to anticipate cyclic environmental changes and adapt their behavior and physiology. Components of the molecular clock are largely conserved across a broad range of species but appreciable diversity in clock structure and function is also present especially in invertebrates. The present work aimed at identify and characterize molecular clockwork components in relationship with the monitoring of valve activity behavior in the oyster Crassostrea gigas. Results provided the characterization of most of canonical clock gene including clock, bmal/cycle, period, timeless, vertebrate-type cry, rev-erb, ror as well as other members of the cryptochrome/photolyase family (plant-like cry, 6-4 photolyase). Analyses of transcriptional variations of clock candidates in oysters exposed to light / dark regime and to constant darkness led to the generation of a putative and original clockwork model in C. gigas, intermediate of described systems in vertebrates and insects. This study is the first characterization of a mollusk clockwork. It constitutes essential bases to understand interactions of the different components of the molecular clock in C. gigas as well as the global mechanisms associated to the generation and the synchronization of biological rhythms in oysters.
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