Evidence map›Paper›PMID 28072468›Full record

ArticleBiometrics2017

A multi-dimensional functional principal components analysis of EEG data.

Kyle Hasenstab, Aaron Scheffler, Donatello Telesca, Catherine A Sugar, Shafali Jeste, Charlotte DiStefano, Damla Şentürk

Open access · greenAbstract read
In one paragraph

Article in Biometrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
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  7. Guaranteed Functional Tensor Singular Value Decomposition.Journal of the American Statistical Association · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Application of EEG in migraine.Frontiers in human neuroscience · 2023
    Review
  12. Article
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  15. Review
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  17. Article
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  20. Inferring Brain Signals Synchronicity from a Sample of EEG Readings.Journal of the American Statistical Association · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kyle HasenstabDepartment of Statistics, University of California, Los Angeles, California 90095, U.S.A.
Aaron SchefflerDepartment of Biostatistics, University of California, Los Angeles, California 90095, U.S.A.
Donatello TelescaDepartment of Biostatistics, University of California, Los Angeles, California 90095, U.S.A.
Catherine A SugarDepartment of Statistics, University of California, Los Angeles, California 90095, U.S.A.
Shafali JesteDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California 90095, U.S.A.
Charlotte DiStefanoDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, California 90095, U.S.A.
Damla ŞentürkDepartment of Statistics, University of California, Los Angeles, California 90095, U.S.A.
University of California, Los Angeles · USNeurobehavioral Systems · US

Funding

UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yvonne Yu-Hsuan Chen · 2017 to 2026
$25.2M
A unified longitudinal functional data framework for the analysis of complex biomedical dataR01GM111378 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SENTURK, DAMLA, SUGAR, CATHERINE ANN · 2015 to 2018
$1.4M
NCI NIH HHS P50 CA211015NIGMS NIH HHS R01 GM111378
6 · The paper itself

Abstract

The electroencephalography (EEG) data created in event-related potential (ERP) experiments have a complex high-dimensional structure. Each stimulus presentation, or trial, generates an ERP waveform which is an instance of functional data. The experiments are made up of sequences of multiple trials, resulting in longitudinal functional data and moreover, responses are recorded at multiple electrodes on the scalp, adding an electrode dimension. Traditional EEG analyses involve multiple simplifications of this structure to increase the signal-to-noise ratio, effectively collapsing the functional and longitudinal components by identifying key features of the ERPs and averaging them across trials. Motivated by an implicit learning paradigm used in autism research in which the functional, longitudinal, and electrode components all have critical interpretations, we propose a multidimensional functional principal components analysis (MD-FPCA) technique which does not collapse any of the dimensions of the ERP data. The proposed decomposition is based on separation of the total variation into subject and subunit level variation which are further decomposed in a two-stage functional principal components analysis. The proposed methodology is shown to be useful for modeling longitudinal trends in the ERP functions, leading to novel insights into the learning patterns of children with Autism Spectrum Disorder (ASD) and their typically developing peers as well as comparisons between the two groups. Finite sample properties of MD-FPCA are further studied via extensive simulations.

Indexed as

ElectroencephalographyAutism Spectrum DisorderEvoked PotentialsHumansPrincipal Component AnalysisSignal-To-Noise RatioElectroencephalographyEvent-related potentials dataFunctional data analysisMultilevel functional principal components

Identifiers

PMID28072468
PMCPMC5517364
OpenAlexW2570899667

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.