Evidence map›Paper›PMID 28072413›Full record

ArticleTranslational psychiatry2017

Decreased hippocampal translocator protein (18 kDa) expression in alcohol dependence: a [

N J Kalk, Q Guo, D Owen, R Cherian, D Erritzoe, A Gilmour, A S Ribeiro, J McGonigle, A Waldman, P Matthews and 6 more

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. MAO-B status in alcohol use disorder: a [Molecular psychiatry · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Molecular Imaging Studies of Alcohol Use Disorder.Current topics in behavioral neurosciences · 2025
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

N J KalkNational Addictions Centre, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
Q GuoNeuroimaging Department, Kings College London, London, UK.
D OwenDivision of Brain Sciences, Imperial College London, London, UK.
R CherianWest London Mental Health NHS Trust, London, UK.
D ErritzoeCentre for Neuropsychopharmacology, Imperial College London, London, UK.
A GilmourCentre for Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
A S RibeiroCentre for Neuropsychopharmacology, Imperial College London, London, UK.
J McGonigleCentre for Neuropsychopharmacology, Imperial College London, London, UK.
A WaldmanDivision of Brain Sciences, Imperial College London, London, UK.
P MatthewsDivision of Brain Sciences, Imperial College London, London, UK.
J CavanaghInstitute of Health and Well-being, University of Glasgow, Glasgow, UK.
I McInnesCentre for Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
K DarCentral and North West London NHS Trust, London, UK.
R GunnImanova Limited, London, UK.
E A RabinerImanova Limited, London, UK.
A R Lingford-HughesCentre for Neuropsychopharmacology, Imperial College London, London, UK.
Imperial College London · GBUniversity of Glasgow · GBKing's College London · GBLivaNova (United Kingdom) · GBWest London Mental Health NHS Trust · GB

Funding

Medical Research Council G0900897Medical Research Council MR/N008219/1Medical Research Council MR/N026934/1Wellcome Trust
6 · The paper itself

Abstract

Repeated withdrawal from alcohol is clinically associated with progressive cognitive impairment. Microglial activation occurring during pre-clinical models of alcohol withdrawal is associated with learning deficits. We investigated whether there was microglial activation in recently detoxified alcohol-dependent patients (ADP), using [

Indexed as

AcetamidesAlcoholismAstrocytesCarbon RadioisotopesCase-Control StudiesDrug ContaminationFemaleHippocampusHumansMaleMicrogliaMiddle AgedPositron-Emission TomographyPyridinesRadiopharmaceuticalsReceptors, GABAAcetamidesCarbon RadioisotopesN-(2-methoxybenzyl)-N-(4-phenoxypyridin-3-yl)acetamidePyridinesRadiopharmaceuticalsReceptors, GABATSPO protein, human

Identifiers

PMID28072413
PMCPMC5545729
OpenAlexW2570417321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.