Evidence map›Paper›PMID 28072390›Full record

ArticleeLife2017

A molecular portrait of maternal sepsis from Byzantine Troy.

Alison M Devault, Tatum D Mortimer, Andrew Kitchen, Henrike Kiesewetter, Jacob M Enk, G Brian Golding, John Southon, Melanie Kuch, Ana T Duggan, William Aylward and 11 more

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
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  4. A 16Communications biology · 2022
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Lateral Gene Transfer Shapes Diversity ofFrontiers in cellular and infection microbiology · 2020
    Article
  11. Article
  12. Multidisciplinarity in Microbiome Research: A Challenge and Opportunity to Rethink Causation, Variability, and Scale.BioEssays : news and reviews in molecular, cellular and developmental biology · 2019
    Review
  13. Review
  14. Article
  15. Review
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Alison M DevaultMcMaster Ancient DNA Centre, Department of Anthropology, McMaster University, Hamilton, Canada.
Tatum D MortimerDepartment of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, United States.ORCID 0000-0001-6255-690X
Andrew KitchenDepartment of Anthropology, University of Iowa, Iowa City, United States.
Henrike KiesewetterProject Troia, Institute of Prehistory, Early History, and Medieval Archaeology, Tübingen University, Tübingen, Germany.
Jacob M EnkMcMaster Ancient DNA Centre, Department of Anthropology, McMaster University, Hamilton, Canada.
G Brian GoldingDepartment of Biology, McMaster University, Hamilton, Canada.
John SouthonKeck Carbon Cycle Accelerator Mass Spectrometer, Earth Systems Science Department, University of California, Irvine, United States.
Melanie KuchMcMaster Ancient DNA Centre, Department of Anthropology, McMaster University, Hamilton, Canada.
Ana T DugganMcMaster Ancient DNA Centre, Department of Anthropology, McMaster University, Hamilton, Canada.
William AylwardMolecular Archaeology Laboratory, Biotechnology Center, University of Wisconsin-Madison, Madison, United States.
Shea N GardnerLawrence Livermore National Laboratory, Livermore, United States.
Jonathan E AllenLawrence Livermore National Laboratory, Livermore, United States.
Andrew M KingMichael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada.
Gerard WrightMichael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada.
Makoto KurodaLaboratory of Bacterial Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases, Tokyo, Japan.
Kengo KatoLaboratory of Bacterial Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases, Tokyo, Japan.
Derek Eg BriggsDepartment of Geology and Geophysics, Yale University, New Haven, United States.
Gino FornaciariDivision of Paleopathology, Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Edward C HolmesMarie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, Australia.ORCID 0000-0001-9596-3552
Hendrik N PoinarMcMaster Ancient DNA Centre, Department of Anthropology, McMaster University, Hamilton, Canada.
Caitlin S PepperellDepartment of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, United States.ORCID 0000-0002-6324-1333

Funding

GRADUATE TRAINING IN MOLECULAR BIOSCIENCEST32GM007215 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 1985 to 2018
$22.5M
Drifting to victory: resolving the paradox of M.tuberculosis evolutionR01AI113287 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI Caitlin S Pepperell · 2015 to 2026
$6.5M
NIAID NIH HHS R01 AI113287NIGMS NIH HHS T32 GM007215
6 · The paper itself

Abstract

Pregnancy complications are poorly represented in the archeological record, despite their importance in contemporary and ancient societies. While excavating a Byzantine cemetery in Troy, we discovered calcified abscesses among a woman's remains. Scanning electron microscopy of the tissue revealed 'ghost cells', resulting from dystrophic calcification, which preserved ancient maternal, fetal and bacterial DNA of a severe infection, likely chorioamnionitis.

Indexed as

FossilsAbscessDNA, BacterialFemaleGardnerella vaginalisGram-Positive Bacterial InfectionsHumansMicroscopy, Electron, ScanningPregnancyPregnancy Complications, InfectiousStaphylococcus saprophyticusDNA, BacterialAncient DNAchorioamnionitisevolutionevolutionary biologyGardnerella vaginalisgenomicshumaninfectious diseasemicrobiologyStaphylococcus saprophyticus

Identifiers

PMID28072390
PMCPMC5224923

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.