Evidence map›Paper›PMID 28071964›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017

Hypercapnia is essential to reduce the cerebral oxidative metabolism during extreme apnea in humans.

Anthony R Bain, Philip N Ainslie, Otto F Barak, Ryan L Hoiland, Ivan Drvis, Tanja Mijacika, Damian M Bailey, Antoinette Santoro, Daniel K DeMasi, Zeljko Dujic and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. A dive into the physiological responses to maximal apneas, OEuropean journal of applied physiology · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Hypoxemia increases blood-brain barrier permeability during extreme apnea in humans.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Cerebral metabolism and vascular reactivity during breath-hold and hypoxic challenge in freedivers and healthy controls.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Anthony R Bain1 Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada.
Philip N Ainslie1 Centre for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada.
Otto F Barak2 School of Medicine, University of Split, Split, Croatia.
Ryan L Hoiland3 Faculty of Medicine, University of Novi Sad, Serbia.
Ivan Drvis4 School of Kinesiology, University of Zagreb, Zagreb, Croatia.
Tanja Mijacika2 School of Medicine, University of Split, Split, Croatia.
Damian M Bailey5 Faculty of Life Sciences and Education, University of South Wales, Glamorgan, UK.
Antoinette Santoro6 Duke University Medical Center, Durham, NC, USA.
Daniel K DeMasi6 Duke University Medical Center, Durham, NC, USA.
Zeljko Dujic2 School of Medicine, University of Split, Split, Croatia.
David B MacLeod6 Duke University Medical Center, Durham, NC, USA.
Duke Medical Center · USUniversity of Split · HRUniversity of British Columbia · CAUniversity of Novi Sad · RSUniversity of South Wales · GBUniversity of Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cerebral metabolic rate of oxygen (CMRO

Indexed as

Oxidative StressAdultApneaBlood Flow VelocityBreath HoldingCerebral CortexCerebrovascular CirculationFemaleHumansHypercapniaHypoxiaJugular VeinsLactic AcidMaleOxygenLactic AcidOxygenbrain metabolismbreath-holdingcerebral lactate releasecerebral nonoxidative metabolismHypoxia

Identifiers

PMID28071964
PMCPMC5584699
OpenAlexW2567870749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.