Evidence map›Paper›PMID 28071910›Full record

ArticleThe journal of physical chemistry. B2017

Direct Measurement of the Effect of Cholesterol and 6-Ketocholestanol on the Membrane Dipole Electric Field Using Vibrational Stark Effect Spectroscopy Coupled with Molecular Dynamics Simulations.

Rebika Shrestha, Cari M Anderson, Alfredo E Cardenas, Ron Elber, Lauren J Webb

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of physical chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Ion Adsorption at Surfaces from Local and Global Electroneutrality Constraints.Langmuir : the ACS journal of surfaces and colloids · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rebika ShresthaDepartment of Chemistry, ‡Institute for Cell and Molecular Biology, §Center for Nano- and Molecular Science and Technology, and ∥Institute for Computational Engineering and Sciences, The University of Texas at Austin , Austin, Texas 78712, United States.
Cari M AndersonDepartment of Chemistry, ‡Institute for Cell and Molecular Biology, §Center for Nano- and Molecular Science and Technology, and ∥Institute for Computational Engineering and Sciences, The University of Texas at Austin , Austin, Texas 78712, United States.
Alfredo E CardenasDepartment of Chemistry, ‡Institute for Cell and Molecular Biology, §Center for Nano- and Molecular Science and Technology, and ∥Institute for Computational Engineering and Sciences, The University of Texas at Austin , Austin, Texas 78712, United States.
Ron ElberDepartment of Chemistry, ‡Institute for Cell and Molecular Biology, §Center for Nano- and Molecular Science and Technology, and ∥Institute for Computational Engineering and Sciences, The University of Texas at Austin , Austin, Texas 78712, United States.ORCID 0000-0001-7849-415X
Lauren J WebbDepartment of Chemistry, ‡Institute for Cell and Molecular Biology, §Center for Nano- and Molecular Science and Technology, and ∥Institute for Computational Engineering and Sciences, The University of Texas at Austin , Austin, Texas 78712, United States.ORCID 0000-0001-9999-5500
The University of Texas at Austin · US

Funding

LONG TIME DYNAMICS OF BIOMOLECULESR01GM059796 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI ELBER, RON · 2000 to 2021
$5.7M
Modeling Membrane Dynamics and PermeationR01GM111364 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI CARDENAS, ALFREDO, ELBER, RON · 2016 to 2023
$2.5M
NIGMS NIH HHS R01 GM059796NIGMS NIH HHS R01 GM111364
6 · The paper itself

Abstract

Biological membranes are heterogeneous structures with complex electrostatic profiles arising from lipids, sterols, membrane proteins, and water molecules. We investigated the effect of cholesterol and its derivative 6-ketocholestanol (6-kc) on membrane electrostatics by directly measuring the dipole electric field (F⃗

Indexed as

Molecular Dynamics SimulationStatic ElectricityCholesterolElectromagnetic FieldsKetocholesterolsLipid BilayersSpectrophotometry, InfraredSurface PropertiesVibrationWater6-ketocholestanolCholesterolKetocholesterolsLipid BilayersWater

Identifiers

PMID28071910
PMCPMC5398937
OpenAlexW2570843401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.