Evidence map›Paper›PMID 28071737›Full record

ArticleScientific reports2017

Efficient biosynthesis of a Cecropin A-melittin mutant in Bacillus subtilis WB700.

Shengyue Ji, Weili Li, Abdul Rasheed Baloch, Meng Wang, Hengxin Li, Binyun Cao, Hongfu Zhang

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Therapeutic Bioactivity Exerted by theMolecules (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Establishment of the CRISPR-Cpf1 gene editing system inSynthetic and systems biotechnology · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Antifungal Peptides as Therapeutic Agents.Frontiers in cellular and infection microbiology · 2020
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Shengyue JiInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100094, China.
Weili LiInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100094, China.
Abdul Rasheed BalochCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.
Meng WangCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.
Hengxin LiInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100094, China.
Binyun CaoCollege of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Hongfu ZhangInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100094, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficient production of antimicrobial peptides (AMPs) for clinical applications has attracted the attention of the scientific community. To develop a novel microbial cell factory for the efficient biosynthesis of a cecropin A-melittin mutant (CAM-W), a recombinant Bacillus subtilis WB700 expression system was genetically modified with a novel vector, including a fusion gene encoding CAM-W, the autoprotease EDDIE and the signal peptide SacB under the control of the maltose-inducible promoter P

Indexed as

Antimicrobial Cationic PeptidesBacillus subtilisMelittenMicrobial Sensitivity TestsMutant ProteinsPlasmidsRecombinant ProteinsRecombination, GeneticAntimicrobial Cationic Peptidescecropin AMelittenMutant ProteinsRecombinant Proteins

Identifiers

PMID28071737
PMCPMC5223193

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.