Evidence map›Paper›PMID 28071711›Full record

ArticleScientific reports2017

Transient anhedonia phenotype and altered circadian timing of behaviour during night-time dim light exposure in Per3

Bruno Jacson Martynhak, Alexandra L Hogben, Panos Zanos, Polymnia Georgiou, Roberto Andreatini, Ian Kitchen, Simon N Archer, Malcolm von Schantz, Alexis Bailey, Daan R van der Veen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Disturbances of Hormonal Circadian Rhythms by Light Pollution.International journal of molecular sciences · 2023
    Review
  3. Vivarium Lighting as an Important Extrinsic Factor Influencing Animal-based Research.Journal of the American Association for Laboratory Animal Science : JAALAS · 2023
    Review
  4. Article
  5. Disrupted circadian rhythms and mental health.Handbook of clinical neurology · 2021
    Review
  6. Article
  7. Circadian rhythm disruption and mental health.Translational psychiatry · 2020
    Review
  8. Circadian regulation of depression: A role for serotonin.Frontiers in neuroendocrinology · 2019
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Bruno Jacson MartynhakFaculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Alexandra L HogbenFaculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Panos ZanosFaculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Polymnia GeorgiouFaculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Roberto AndreatiniDepartment of Pharmacology, Federal University of Paraná, Curitiba, Paraná, Brazil.
Ian KitchenFaculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Simon N ArcherFaculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Malcolm von SchantzFaculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Alexis BaileyFaculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
Daan R van der VeenFaculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
University of Surrey · GBUniversidade Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Industrialisation greatly increased human night-time exposure to artificial light, which in animal models is a known cause of depressive phenotypes. Whilst many of these phenotypes are 'direct' effects of light on affect, an 'indirect' pathway via altered sleep-wake timing has been suggested. We have previously shown that the Period3 gene, which forms part of the biological clock, is associated with altered sleep-wake patterns in response to light. Here, we show that both wild-type and Per3

Indexed as

AnhedoniaAnimalsBrain-Derived Neurotrophic FactorCircadian ClocksCircadian RhythmGene Expression RegulationHippocampusHumansImipramineMiceMice, KnockoutMotor ActivityPeriod Circadian ProteinsPhotoperiodSleepSleep Wake DisordersBrain-Derived Neurotrophic FactorImipraminePer3 protein, mousePeriod Circadian Proteins

Identifiers

PMID28071711
PMCPMC5223197
OpenAlexW2570210165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.