Trial reportScientific reports2017
Effect of shortened sleep on energy expenditure, core body temperature, and appetite: a human randomised crossover trial.
Trial report in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 59 citations in OpenAlex.
- Late, but Not Early, Night Sleep Loss Compromises Neuroendocrine Appetite Regulation and the Desire for Food.Nutrients · 2023Trial
- Effects of ad libitum food intake, insufficient sleep and weekend recovery sleep on energy balance.Sleep · 2021Trial
- Clamping Cortisol and Testosterone Mitigates the Development of Insulin Resistance during Sleep Restriction in Men.The Journal of clinical endocrinology and metabolism · 2021Trial
- Four nights of sleep restriction suppress the postprandial lipemic response and decrease satiety.Journal of lipid research · 2019Trial
- Influence of sleep restriction on weight loss outcomes associated with caloric restriction.Sleep · 2018Trial
- Examining the Role of Sleep in Body Weight Regulation and Implications for Obesity Treatment: A Narrative Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Machine learning predicts diabetes risk in high-risk populations: analysis of National Health and Nutrition Examination Survey data.Archives of medical science : AMS · 2026Article
- Sleep and circadian effects on the incretin system.Current sleep medicine reports · 2025Article
- Algorithm for transient response of human open-circuit whole-room indirect calorimetry: A review and future perspective.Physiological reports · 2025Review
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- Gender differences in the association between sleep duration and diabetes in Chinese adults.Frontiers in endocrinology · 2025Article
- Changes in Body Temperature Patterns Are Predictive of Mortality in Septic Shock: An Observational Study.Biology · 2023Article
- Connecting insufficient sleep and insomnia with metabolic dysfunction.Annals of the New York Academy of Sciences · 2023Review
- Healthy Sleep Every Day Keeps the Doctor Away.International journal of environmental research and public health · 2022Review
- Modest sleep restriction does not influence steps, physical activity intensity or glucose tolerance in obese adults.Journal of sleep research · 2021Article
- Effects of sleep deprivation on sarcopenia and obesity: A narrative review of randomized controlled and crossover trials.Journal of frailty, sarcopenia and falls · 2021Article
- Dissociation of Subjective and Objective Alertness During Prolonged Wakefulness.Nature and science of sleep · 2021Article
- Rapidly declining body temperature in a tropical human population.Science advances · 2020Article
- Sleep and thermoregulation.Current opinion in physiology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effects of sleep restriction on energy metabolism and appetite remain controversial. We examined the effects of shortened sleep duration on energy metabolism, core body temperature (CBT), and appetite profiles. Nine healthy men were evaluated in a randomised crossover study under two conditions: a 3.5-h sleep duration and a 7-h sleep duration for three consecutive nights followed by one 7-h recovery sleep night. The subjects' energy expenditure (EE), substrate utilisation, and CBT were continually measured for 48 h using a whole-room calorimeter. The subjects completed an appetite questionnaire every hour while in the calorimeter. Sleep restriction did not affect total EE or substrate utilisation. The 48-h mean CBT decreased significantly during the 3.5-h sleep condition compared with the 7-h sleep condition (7-h sleep, 36.75 ± 0.11 °C; 3.5-h sleep, 36.68 ± 0.14 °C; p = 0.016). After three consecutive nights of sleep restriction, fasting peptide YY levels and fullness were significantly decreased (p = 0.011), whereas hunger and prospective food consumption were significantly increased, compared to those under the 7-h sleep condition. Shortened sleep increased appetite by decreasing gastric hormone levels, but did not affect EE, suggesting that greater caloric intake during a shortened sleep cycle increases the risk of weight gain.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.