Evidence map›Paper›PMID 28070838›Full record

ArticleLa Radiologia medica2017

Late toxicity, evolving radiotherapy techniques, and quality of life in nasopharyngeal carcinoma.

Luciana Lastrucci, Silvia Bertocci, Vittorio Bini, Simona Borghesi, Roberta De Majo, Andrea Rampini, Paola Pernici, Pietro Giovanni Gennari

Abstract read
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In one paragraph

Article in La Radiologia medica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Radiotherapy-induced dysphagia and its impact on quality of life in patients with nasopharyngeal carcinoma.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
    Article
  8. Hearing loss and tinnitus in survivors with chemotherapy-induced neuropathy.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Luciana LastrucciUnit of Radiation Oncology, San Donato Hospital, Arezzo, Italy. luciana.lastrucci@uslsudest.toscana.it.ORCID http://orcid.org/0000-0002-2734-9929
Silvia BertocciUnit of Radiation Oncology, San Donato Hospital, Arezzo, Italy.
Vittorio BiniDepartment of Medicine Section of Internal Medicine Endocrine and Metabolic Sciences, University of Perugia, Perugia, Italy.
Simona BorghesiUnit of Radiation Oncology, San Donato Hospital, Arezzo, Italy.
Roberta De MajoUnit of Radiation Oncology, San Donato Hospital, Arezzo, Italy.
Andrea RampiniUnit of Radiation Oncology, San Donato Hospital, Arezzo, Italy.
Paola PerniciUnit of Radiation Oncology, San Donato Hospital, Arezzo, Italy.
Pietro Giovanni GennariUnit of Radiation Oncology, San Donato Hospital, Arezzo, Italy.
Ospedale San Donato · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyze quality of life (QoL) and functional state (FS) by patient-reported outcome (PRO) questionnaires (FACT-G, FACT-NP, PSS-HN, XeQOLS, and EQ-5D-3L) in long-term survivors nasopharyngeal carcinoma (NPC) treated with conventional radiotherapy (RT) and intensity modulated radiotherapy (IMRT).

methods25 patients answered to five questionnaires about QoL and FS. All patients were assessed also for late toxicity.

resultsFunctional Assessment of Cancer Therapy-General (FACT-G) and Performance Status Scale Head and Neck (PSS-HN) scores were significantly elevated (better QoL) in age <50 years (p = 0.03). PSS-HN score was higher in IMRT group. The observed xerostomia was lower in the IMRT group and in patients who received conventional RT had worse QoL according to XeQOLS (University of Michigan Xerostomia-Related Quality of Life Scale) score questionnaire. Lower PSS-HN score and higher XeQOLS score were significantly related with the late xerostomia (p = 0.009 and 0.002, respectively).

conclusionsOur preliminary data suggest that age, older techniques, xerostomia, and hearing loss are negative predictors of QoL.

Indexed as

Quality of LifeAdolescentAdultAgedAged, 80 and overCarcinomaFemaleHumansKaplan-Meier EstimateMaleMiddle AgedNasopharyngeal CarcinomaNasopharyngeal NeoplasmsNeoplasm StagingRadiation InjuriesRadiotherapy DosageNasopharyngeal neoplasmQuality of lifeRadiotherapyXerostomia

Identifiers

PMID28070838
OpenAlexW2567961751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.