Evidence map›Paper›PMID 28070744›Full record

ArticleInternational ophthalmology2018

Changes in patterns of uveitis at a tertiary referral center in Northern Italy: analysis of 990 consecutive cases.

Cimino Luca, Aldigeri Raffaella, Marchi Sylvia, Mastrofilippo Valentina, Viscogliosi Fabiana, Coassin Marco, Soldani Annamaria, Savoldi Luisa, De Fanti Alessandro, Belloni Lucia and 6 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in International ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Identification of markers predicting clinical course in patients with Behcet disease by combination of machine learning and unbiased clustering analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  3. Epidemiology, clinical features, and classification of 3,404 patients with uveitis: Colombian Uveitis Multicenter Study (COL-UVEA).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  4. Pattern of uveitis in a referral ophthalmology center in Northeastern Thailand.Journal of ophthalmic inflammation and infection · 2024
    Article
  5. Treatment of uveitis and scleritis patients in Malaysia.International journal of ophthalmology · 2024
    Article
  6. Article
  7. Article
  8. Sarcoidosis-Related Uveitis: A Review.Journal of clinical medicine · 2023
    Review
  9. A new look into uveitis in Colombia: changes in distribution patterns and clinical characteristics over the last 25 years.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  10. Article
  11. Impact of Climate Change on Eye Diseases and Associated Economical Costs.International journal of environmental research and public health · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. TNF-α in Uveitis: From Bench to Clinic.Frontiers in pharmacology · 2021
    Review
  16. Article
  17. Immunological tests and their interpretation in uveitis.Indian journal of ophthalmology · 2020
    Review
  18. Article
  19. Comparison of visual field defect progression in secondary Glaucoma due to anterior uveitis caused by three types of herpes viruses.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Cimino LucaImmunology Eye Unit, Eye Department, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy. cimino.luca@asmn.re.it.ORCID http://orcid.org/0000-0001-7956-9950
Aldigeri RaffaellaDepartment of Clinical and Experimental Medicine, University of Parma, Parma, Italy.
Marchi SylviaImmunology Eye Unit, Eye Department, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy.
Mastrofilippo ValentinaImmunology Eye Unit, Eye Department, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy.
Viscogliosi FabianaImmunology Eye Unit, Eye Department, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy.
Coassin MarcoEye Department, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy.
Soldani AnnamariaImmunology Eye Unit, Eye Department, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy.
Savoldi LuisaScientific Directorate, Arcispedale S.M. Nuova-IRCCS, Reggio Emilia, Italy.
De Fanti AlessandroDepartment of Pediatrics, Arcispedale S. M. Nuova.IRCCS, Reggio Emilia, Italy.
Belloni LuciaClinical Immunology, Allergy and Advanced Biotechnologies Unit, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy.
Zerbini AlessandroClinical Immunology, Allergy and Advanced Biotechnologies Unit, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy.
Parmeggiani MariaClinical Immunology, Allergy and Advanced Biotechnologies Unit, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy.
Chersich MatthewWits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Soriano AlessandraRheumatology Unit, Department of Internal Medicine, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy.
Salvarani CarloRheumatology Unit, Department of Internal Medicine, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy.
Fontana LuigiEye Department, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITAzienda Ospedaliera S.Maria · ITOspedale Santa Maria · ITUniversity of Parma · ITUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe role of uveitis, an uncommon ocular disease, is often neglected in research and treatment of autoimmune conditions. The study described the spectrum of uveitis at a referral center in North Italy, and compared that to a previously published series of patients.

methodsWe reviewed all patients with uveitis diagnosed from 2013 to 2015 at the Immunology Eye Unit, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy. We examined patient characteristics, disease spectrum, and etiologies.

resultsIn total, 990 cases of uveitis were identified, who were mostly female (59%) with a median age at presentation of 44 years (interquartile range = 29-57). Anterior uveitis was most frequent (53.5%), followed by panuveitis (22.8%), posterior (16.2%), and intermediate uveitis (5.5%). Anterior herpetic uveitis (15.6%), Fuchs uveitis (9.7%), and HLA-B27 positive anterior uveitis (7.7%) were the most common specific diagnoses. Compared with the previous series, we observed an increased incidence of uveitis, and a different pattern of diagnoses. Rates of herpetic, HLA-B27 positive uveitis, and presumed ocular tuberculosis were higher, but Fuchs uveitis was less frequent.

conclusionsThe pattern of uveitis appears to be changing, very likely due to population-level increases in infectious diseases, to the availability of new diagnostic tests and to the interdisciplinary approach used in patient diagnosis.

Indexed as

AdultAgedEye InfectionsFemaleHumansIncidenceItalyMaleMiddle AgedPanuveitisTertiary Care CentersUveitisUveitis, AnteriorUveitis, IntermediateEpidemiologyInfectionInterdisciplinary approachItalySystemic diseaseUveitis

Identifiers

PMID28070744
PMCPMC5876414
OpenAlexW2570636132

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.