ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018
Assessment of atherosclerotic plaque calcification using F18-NaF PET-CT.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03233243 (Rosuvastatin Effect on Atherosclerotic Plaque Metabolism - a Subclinical Atherosclerosis Imaging Study With 18F-NaF PET-CT), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Rosuvastatin Effect on Atherosclerotic Plaque Metabolism - a Subclinical Atherosclerosis Imaging Study With 18F-NaF PET-CT
Open the trial in the graphWho cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Vitamin K supplementation and vascular calcification: a systematic review and meta-analysis of randomized controlled trials.Frontiers in nutrition · 2023Pooled it
- Sodium fluoride in cardiovascular disorders: A systematic review.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Pooled it
- The effect of Vitamin-KJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Trial
- Cardiac Imaging in Women with Ischemic Heart Disease.Life (Basel, Switzerland) · 2023Review
- Imaging of heart disease in women: review and case presentation.European journal of nuclear medicine and molecular imaging · 2022Review
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Iterative reconstruction incorporating background correction improves quantification of [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Advances in Quantitative Analysis ofMolecular imaging · 2021Review
- Aortic valve microcalcification and cardiovascular risk: an exploratory study using sodium fluoride in high cardiovascular risk patients.The international journal of cardiovascular imaging · 2020Article
- Atherosclerosis imaging withEuropean journal of nuclear medicine and molecular imaging · 2020Review
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2018. Part 1 of 2: Positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the present study was to evaluate the uptake of F18-NaF by the arterial wall in patients with high cardiovascular (CV) risk profile. The tracer uptake was assessed in relation to gender and the number of CV risk factors. METHODS AND
results25 patients without known CV disease were included and evaluated by PET-CT with F18-NaF: 14 (56%) men and 11 (44%) women. The mean target-to-background ratio (TBR: max SUV/mean blood-pool SUV) but not the corrected uptake per lesion (CUL: max SUV - mean blood-pool SUV) was higher in men than women (TBR: 1.8 ± 0.6 vs 1.7 ± 0.2; P = 0.04; CUL: 0.7 ± 0.3 vs W 0.6 ± 0.1; P = 0.4). Patients with >3 CV risk factors had higher CUL (0.8 ± 0.1 vs 0.6 ± 0.2; P = 0.01) but not TBR (1.8 ± 0.2 vs 1.7 ± 0.6; P = 0.7) than patients with <3 risk factors.
conclusionsThe TBR but not CUL is higher in men than women while the CUL but not TBR is related to the number of CV risk factors. These results are hypothesis-generating and require validation in larger studies.
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Registered trials
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