Evidence map›Paper›PMID 28070703›Full record

ArticleMetabolic brain disease2017

NMR-based metabolomics reveals brain region-specific metabolic alterations in streptozotocin-induced diabetic rats with cognitive dysfunction.

Hong Zheng, Qiuting Lin, Dan Wang, Pengtao Xu, Liangcai Zhao, Wenyi Hu, Guanghui Bai, Zhihan Yan, Hongchang Gao

Abstract read
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In one paragraph

Article in Metabolic brain disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hong ZhengSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Qiuting LinSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Dan WangSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Pengtao XuSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Liangcai ZhaoSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Wenyi HuSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China.
Guanghui BaiRadiology Department of the Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, 325027, China.
Zhihan YanRadiology Department of the Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, 325027, China.
Hongchang GaoSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, 325035, China. gaohc27@wmu.edu.cn.
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) can result in cognitive dysfunction, but its potential metabolic mechanisms remain unclear. In the present study, we analyzed the metabolite profiling in eight different brain regions of the normal rats and the streptozotocin (STZ)-induced diabetic rats accompanied by cognitive dysfunction using a

Indexed as

AnimalsBrain ChemistryCognition DisordersDiabetes Mellitus, ExperimentalMagnetic Resonance SpectroscopyMaleMaze LearningMetabolic Networks and PathwaysMetabolomicsRats, Sprague-DawleyBrain metabolismCognitive declineDiabetes mellitusHippocampusNeurotransmitter

Identifiers

PMID28070703
OpenAlexW2570987822

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.