Evidence map›Paper›PMID 28070684›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2017

A pilot cadaveric study of temperature and adjacent tissue changes after exposure of magnetic-controlled growing rods to MRI.

Selina Poon, Ryan Nixon, Stephen Wendolowski, Rachel Gecelter, Yen Hsun Chen, Jon-Paul DiMauro, Terry Amaral, Adam Graver, Daniel A Grande

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Selina PoonDepartment of Orthopaedics, Shriners Hospitals for Children, 3160 Geneva Street, Los Angeles, CA, 90020, USA. spoon@shrinenet.org.
Ryan NixonDepartment of Pediatric Orthopaedics, Cohen Children's Medical Center, Lake Success, NY, USA.
Stephen WendolowskiDepartment of Pediatric Orthopaedics, Cohen Children's Medical Center, Lake Success, NY, USA.
Rachel GecelterDepartment of Pediatric Orthopaedics, Cohen Children's Medical Center, Lake Success, NY, USA.
Yen Hsun ChenDepartment of Pediatric Orthopaedics, Cohen Children's Medical Center, Lake Success, NY, USA.
Jon-Paul DiMauroDepartment of Pediatric Orthopaedics, Cohen Children's Medical Center, Lake Success, NY, USA.
Terry AmaralDepartment of Pediatric Orthopaedics, Cohen Children's Medical Center, Lake Success, NY, USA.
Adam GraverDepartment of Pediatric Orthopaedics, Cohen Children's Medical Center, Lake Success, NY, USA.
Daniel A GrandeOrthopedic Research Laboratory, The Feinstein Institute for Medical Research, Manhasset, NY, USA.
Cohen Children's Medical Center · USFeinstein Institute for Medical Research · USShriners Hospitals for Children · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo test for possible thermal injury and tissue damage caused by magnetic-controlled growing rods (MCGRs) during MRI scans.

methodsThree fresh frozen cadavers were utilized. Four MRI scans were performed: baseline, after spinal hardware implantation, and twice after MCGR implantation. Cross connectors were placed at the proximal end and at the distal end of the construct, making a complete circuit hinged at those two points. Three points were identified as potential sites for significant heating: adjacent to the proximal and distal cross connectors and adjacent to the actuators. Data collected included tissue temperatures at baseline (R1), after screw insertion (R2), and twice after rod insertions (R3 and R4). Tissue samples were taken and stained for signs of heat damage.

resultsThere was a slight change in tissue temperature in the regions next to the implants between baseline and after each scan. Average temperatures (°C) increased by 0.94 (0.16-1.63) between R1 and R2, 1.6 (1.23-1.97) between R2 and R3, and 0.39 (0.03-0.83) between R3 and R4. Subsequent histological analysis revealed no signs of heat induced damage.

conclusionRecurrent MRI scans of patients with MCGRs may be necessary over the course of treatment. When implanted into human cadaveric tissue, these rods appear to not be a risk to the patient with respect to heating or tissue damage. Further in vivo study is warranted. LEVEL OF EVIDENCE: N/A.

Indexed as

Hot TemperatureHumansMagnetic Resonance ImagingMagnetsOsteogenesis, DistractionPilot ProjectsScoliosisEarly onset scoliosisGrowing rodsMagnetic-controlled growing rodsMagnetic resonance imagingScoliosis

Identifiers

PMID28070684
OpenAlexW2570503675

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.