Evidence map›Paper›PMID 28070505›Full record

ArticleBioMed research international2016

The Association between NOS3 Gene Polymorphisms and Hypoxic-Ischemic Encephalopathy Susceptibility and Symptoms in Chinese Han Population.

Yongqin Wu, Zhiling Zhu, Xiaoxia Fang, Ling Yin, Yuxia Liu, Shouxia Xu, Aixue Li

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants.American journal of physiology. Lung cellular and molecular physiology · 2018
    Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Antioxidants (Basel, Switzerland) · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Genetic Factors of Nitric Oxide's System in Psychoneurologic Disorders.International journal of molecular sciences · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yongqin WuDepartment of Nursing, Xinxiang Central Hospital, Affiliated Central Hospital, Xinxiang Medical University, No. 56, Jinsui Road, Xinxiang 453000, China.
Zhiling ZhuDepartment of Nursing, Xinxiang Central Hospital, Affiliated Central Hospital, Xinxiang Medical University, No. 56, Jinsui Road, Xinxiang 453000, China.ORCID 0000-0001-7782-4639
Xiaoxia FangDepartment of Nursing, Xinxiang Central Hospital, Affiliated Central Hospital, Xinxiang Medical University, No. 56, Jinsui Road, Xinxiang 453000, China.
Ling YinDepartment of Pediatrics, Xinxiang Central Hospital, Affiliated Central Hospital, Xinxiang Medical University, No. 56, Jinsui Road, Xinxiang 453000, China.
Yuxia LiuDepartment of Pediatrics, Xinxiang Central Hospital, Affiliated Central Hospital, Xinxiang Medical University, No. 56, Jinsui Road, Xinxiang 453000, China.
Shouxia XuDepartment of Nursing, Xinxiang Central Hospital, Affiliated Central Hospital, Xinxiang Medical University, No. 56, Jinsui Road, Xinxiang 453000, China.
Aixue LiDepartment of Pediatric Rehabilitation, Xinxiang Central Hospital, Affiliated Central Hospital, Xinxiang Medical University, No. 56, Jinsui Road, Xinxiang 453000, China.
Xinxiang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial NOS (NOS3) has a potential role in the prevention of neuronal injury in hypoxic-ischemic encephalopathy (HIE). Thus, we aimed to explore the association between NOS3 gene polymorphisms and HIE susceptibility and symptoms in a Chinese Han population. Three single nucleotide polymorphisms (SNPs) in the NOS3 gene, rs1800783, rs1800779, and rs2070744, were detected in 226 children with HIE and 212 healthy children in a Chinese Han population. Apgar scores and magnetic resonance image scans were used to estimate the symptoms and brain damage. The association analyses were conducted by using SNPStats and SPSS 18.0 software. The genotype and allele distributions of rs1800779 and rs1799983 displayed no significant differences between the patients and the controls, while the rs2070744 allele distribution was significantly different (corrected

Indexed as

Polymorphism, Single NucleotideAllelesApgar ScoreAsian PeopleBirth WeightBrainCase-Control StudiesChild, PreschoolChinaFemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHaplotypesHumansHypoxia-Ischemia, BrainNitric Oxide Synthase Type IIINOS3 protein, human

Identifiers

PMID28070505
PMCPMC5192303
OpenAlexW2562022755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.