Evidence map›Paper›PMID 28070451›Full record

ArticleFatigue : biomedicine, health & behavior2016

Mortality in Patients with Myalgic Encephalomyelitis and Chronic Fatigue Syndrome.

Stephanie L McManimen, Andrew R Devendorf, Abigail A Brown, Billie C Moore, James H Moore, Leonard A Jason

Abstract read
In one paragraph

Article in Fatigue : biomedicine, health & behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Centralized Pain Diagnoses in Older Adults With and Without Cancer.Journal of pain & palliative care pharmacotherapy · 2026
    Article
  5. Article
  6. An Overview of Severe Myalgic Encephalomyelitis.Journal of clinical medicine · 2026
    Review
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  8. Review
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stephanie L McManimenCenter for Community Research, DePaul University.
Andrew R DevendorfCenter for Community Research, DePaul University.
Abigail A BrownCenter for Community Research, DePaul University.
Billie C MooreCenter for Community Research, DePaul University.
James H MooreCenter for Community Research, DePaul University.
Leonard A JasonCenter for Community Research, DePaul University.

Funding

Pediatric CFS in a Community-Based SampleR01HD072208 · NICHD · DE PAUL UNIVERSITY · PI JASON, LEONARD A · 2013 to 2017
$2.0M
NICHD NIH HHS R01 HD072208
6 · The paper itself

Abstract

backgroundThere is a dearth of research examining mortality in individuals with myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS). Some studies suggest there is an elevated risk of suicide and earlier mortality compared to national norms. However, findings are inconsistent as other researchers have not found significant increases in all-cause mortality for patients.

objectiveThis study sought to determine if patients with ME or CFS are reportedly dying earlier than the overall population from the same cause.

methodsFamily, friends, and caregivers of deceased individuals with ME or CFS were recruited through social media, patient newsletters, emails, and advocate websites. This study analyzed data including cause and age of death for 56 individuals identified as having ME or CFS.

resultsThe findings suggest patients in this sample are at a significantly increased risk of earlier all-cause (

conclusionsThe results suggest there is an increase in risk for earlier mortality in patients with ME and CFS. Due to the small sample size and over-representation of severely ill patients, the findings should be replicated to determine if the directional differences for suicide and cancer mortality are significantly different from the overall U.S. population.

Indexed as

cardiovascularchronic fatigue syndromemortalitymyalgic encephalomyelitissuicide

Identifiers

PMID28070451
PMCPMC5218818

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.