Evidence map›Paper›PMID 28070326›Full record

ArticleFood science & nutrition2017

Effects of cranberry extracts on gene expression in THP-1 cells.

Daniel B Hannon, Jerry T Thompson, Christina Khoo, Vijaya Juturu, John P Vanden Heuvel

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Daniel B HannonDepartment of Veterinary and Biomedical Sciences and Center for Molecular Toxicology and Carcinogenesis Penn State University 325 Life Sciences Building University Park Pennsylvania 16802.
Jerry T ThompsonDepartment of Veterinary and Biomedical Sciences and Center for Molecular Toxicology and Carcinogenesis Penn State University 325 Life Sciences Building University Park Pennsylvania 16802.
Christina KhooOcean Spray Cranberries, Inc. One Ocean Spray Drive Lakeville-Middleboro Massachusetts 02349.
Vijaya JuturuUnitedBio-Med Inc. 102 Hunters Run Dobbs Ferry New York 10502.
John P Vanden HeuvelDepartment of Veterinary and Biomedical Sciences and Center for Molecular Toxicology and Carcinogenesis Penn State University 325 Life Sciences Building University Park Pennsylvania 16802; INDIGO Biosciences Inc.1981 Pine Hall Road State College Pennsylvania 16801.
Pennsylvania State University · USInstitute of Oceanography and Fisheries · HRQ-State Biosciences (United States) · USUnited Biomedical (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cranberry contains high levels of nutrients and bioactive molecules that have health-promoting properties. The purpose of the present studies was to determine if cranberry extracts (CEs) contain phytochemicals that exert anti-inflammatory effects. The human monocytic cell line THP-1 was treated with two CEs (CE and 90MX) and subsequently challenged with Lipopolysaccharides (LPS). Tumor necrosis factor

Indexed as

Gene expressionmacrophagenutrigenomicsproanthocyanidinsreactive oxygen species

Identifiers

PMID28070326
PMCPMC5217924
OpenAlexW2343509140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.