Evidence map›Paper›PMID 28069928›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Functional Organization of Cutaneous and Muscle Afferent Synapses onto Immature Spinal Lamina I Projection Neurons.

Jie Li, Mark L Baccei

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Activation of TRPA1 and TRPM3 triggers CaThe Journal of physiology · 2025
    Article
  2. Cell Type-Dependent Short-Term Plasticity and Dopaminergic Modulation of Sensory Synapses onto Mouse Superficial Dorsal Horn Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Pathophysiology of musculoskeletal pain: a narrative review.Therapeutic advances in musculoskeletal disease · 2021
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Functional Characterization of Lamina X Neurons inFrontiers in cellular neuroscience · 2017
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jie LiPain Research Center, Department of Anesthesiology, University of Cincinnati Medical Center, Cincinnati, Ohio 45267.
Mark L BacceiPain Research Center, Department of Anesthesiology, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 mark.baccei@uc.edu.ORCID 0000-0003-3337-7480
University of Cincinnati · US

Funding

Synaptic Function within Mature Central Pain Networks after Neonatal InjuryR01NS080889 · NINDS · UNIVERSITY OF CINCINNATI · PI Mark L Baccei · 2013 to 2026
$4.5M
Developmental Regulation of Intrinsic Excitability in Spinal Pain NetworksR01NS072202 · NINDS · UNIVERSITY OF CINCINNATI · PI BACCEI, MARK L · 2010 to 2020
$3.4M
NINDS NIH HHS R01 NS072202NINDS NIH HHS R01 NS080889
6 · The paper itself

Abstract

It is well established that sensory afferents innervating muscle are more effective at inducing hyperexcitability within spinal cord circuits compared with skin afferents, which likely contributes to the higher prevalence of chronic musculoskeletal pain compared with pain of cutaneous origin. However, the mechanisms underlying these differences in central nociceptive signaling remain incompletely understood, as nothing is known about how superficial dorsal horn neurons process sensory input from muscle versus skin at the synaptic level. Using a novel

Indexed as

AnimalsAnimals, NewbornFemaleMaleMuscle, SkeletalNeurons, AfferentOrgan Culture TechniquesRatsRats, Sprague-DawleySkinSkin Physiological PhenomenaSpinal Cord Dorsal HornSynapsesSynaptic Potentialsdorsal hornglutamatepainpatch clampprimary afferentsynaptic plasticity

Identifiers

PMID28069928
PMCPMC5299569
OpenAlexW2570926133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.