Evidence map›Paper›PMID 28069919›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Calpain-Mediated Proteolysis of Talin and FAK Regulates Adhesion Dynamics Necessary for Axon Guidance.

Patrick C Kerstein, Kevin M Patel, Timothy M Gomez

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 70 citations in OpenAlex.

  1. Review
  2. Article
  3. Calcium and CaBrain sciences · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Calpain-2-Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Patrick C KersteinDepartment of Neuroscience and.
Kevin M PatelDepartment of Neuroscience and.
Timothy M GomezDepartment of Neuroscience and tmgomez@wisc.edu.ORCID 0000-0002-1515-8228
Society for Neuroscience · USUniversity of Wisconsin–Madison · US

Funding

NEUROSCIENCE TRAINING PROGRAMT32GM007507 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HALLORAN, MARY C · 1985 to 2017
$9.3M
Molecular mechanisms of growth cone invasionR01NS099405 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GOMEZ, TIMOTHY M · 2016 to 2019
$1.4M
Modeling Neural Development Using Human iPSCs from TSC PatientsR21NS088477 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GOMEZ, TIMOTHY M · 2014 to 2015
$414k
Regulation of Axon Guidance by Second MessengerR56NS041564 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GOMEZ, TIMOTHY M · 2015 to 2015
$374k
Mechanisms of mechanical force evoked Ca2+ influx in developing neuronsF31NS074732 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI KERSTEIN, PATRICK C · 2013 to 2014
$67k
NIGMS NIH HHS T32 GM007507NINDS NIH HHS F31 NS074732NINDS NIH HHS R01 NS099405NINDS NIH HHS R21 NS088477NINDS NIH HHS R56 NS041564
6 · The paper itself

Abstract

Guidance of axons to their proper synaptic target sites requires spatially and temporally precise modulation of biochemical signals within growth cones. Ionic calcium (Ca

Indexed as

ProteolysisAnimalsAxon GuidanceCalcium SignalingCalpainCell AdhesionFocal Adhesion Protein-Tyrosine KinasesGrowth ConesHumansSpinal CordTalinXenopus laevisCalpainFocal Adhesion Protein-Tyrosine KinasesTalinextracellular matrixfilopodiaintegrinpaxillinXenopus

Identifiers

PMID28069919
PMCPMC5299572
OpenAlexW2570580129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.