Evidence map›Paper›PMID 28069917›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Dopamine Modulates the Functional Organization of the Orbitofrontal Cortex.

Thorsten Kahnt, Philippe N Tobler

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 67 citations in OpenAlex.

  1. Trial
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  4. Distinct Roles of Dopamine and Noradrenaline in Incidental Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Trial
  5. Beta-Blocker Propranolol Modulates Decision Urgency During Sequential Information Gathering.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Accentuated Paralimbic and Reduced Mesolimbic DThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  14. Review
  15. Frontal lobe fALFF measured from resting-state fMRI as a prognostic biomarker in first-episode psychosis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
  16. A Neuroeconomics Approach to Obesity.Biological psychiatry · 2022
    Review
  17. Article
  18. The reward positivity is sensitive to affective liking.Cognitive, affective & behavioral neuroscience · 2022
    Article
  19. Multi-scale neural decoding and analysis.Journal of neural engineering · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Thorsten KahntDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, and thorsten.kahnt@northwestern.edu.ORCID 0000-0002-3575-2670
Philippe N ToblerDepartment of Economics, Laboratory for Social and Neural Systems Research, University of Zürich, 8006 Zürich, Switzerland.
Northwestern University · USUniversity of Zurich · CH

Funding

Principles of olfactory reward processing in the human brainR01DC015426 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZELANO, CHRISTINA MARIA · 2016 to 2025
$4.4M
NIDCD NIH HHS R01 DC015426
6 · The paper itself

Abstract

Neuromodulators such as dopamine can alter the intrinsic firing properties of neurons and may thereby change the configuration of larger functional circuits. The primate orbitofrontal cortex (OFC) receives dopaminergic input from midbrain nuclei, but the role of dopamine in the OFC is still unclear. Here we tested the idea that dopaminergic activity changes the pattern of connectivity between the OFC and the rest of the brain and thereby reconfigures functional networks in the OFC. To this end, we combined double-blind, placebo-controlled pharmacology [D

Indexed as

AmisulprideDopamineDopamine AntagonistsDouble-Blind MethodHumansMagnetic Resonance ImagingMaleNerve NetPrefrontal CortexRandom AllocationReceptors, Dopamine D2SulpirideAmisulprideDopamineDopamine AntagonistsReceptors, Dopamine D2SulpirideconnectivitydopaminefMRIorbitofrontal cortexparcellation

Identifiers

PMID28069917
PMCPMC5299568
OpenAlexW2568163371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.