Evidence map›Paper›PMID 28069804›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Functional Conversion and Dominance of γδ T Subset in Mouse Experimental Autoimmune Uveitis.

Dongchun Liang, Hong Nian, Hui Shao, Henry J Kaplan, Deming Sun

Abstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Changes of peripheral blood Vδ1 T cells in patients with atherosclerotic cerebral infarction.International journal of clinical and experimental pathology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dongchun LiangDoheny Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90033.
Hong NianTianjin Medical University Eye Hospital, Eye Institute and School of Optometry and Ophthalmology, Tianjin 300384, China; and.ORCID 0000-0002-9983-3410
Hui ShaoDepartment of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, Louisville, KY 40202.
Henry J KaplanDepartment of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, Louisville, KY 40202.
Deming SunDoheny Eye Institute, Department of Ophthalmology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90033; dsun@doheny.org.ORCID 0000-0003-4851-0416

Funding

Role of IL-17+ Autoreactive T Cells in Experimental Autoimmune Uveitis (EAU)R01EY018827 · NEI · DOHENY EYE INSTITUTE · PI SUN, DEMING · 2009 to 2023
$4.8M
Regulation by Gammadelta T Cells of Autoimmune Uveitis (EAU)R01EY022403 · NEI · DOHENY EYE INSTITUTE · PI SUN, DEMING · 2012 to 2015
$1.6M
NEI NIH HHS R01 EY018827NEI NIH HHS R01 EY022403
6 · The paper itself

Abstract

We have previously shown that activated γδ T cells have a much stronger proinflammatory effect in the development of experimental autoimmune uveitis than their nonactivated counterparts. Our present study explored γδ T cell subsets are functionally distinct in autoimmune pathogenesis and determined the pathogenic contribution of biased Vγ4

Indexed as

Lymphocyte ActivationReceptors, Antigen, T-Cell, gamma-deltaAnimalsAutoimmune DiseasesCytokinesMiceMice, Inbred C57BLT-Lymphocyte SubsetsUveitisCytokinesReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID28069804
PMCPMC5296277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.