Evidence map›Paper›PMID 28069650›Full record

ArticleAntimicrobial agents and chemotherapy2017

Evidence To Support Continuation of Statin Therapy in Patients with Staphylococcus aureus Bacteremia.

Aisling R Caffrey, Tristan T Timbrook, Eunsun Noh, George Sakoulas, Steven M Opal, Victor Nizet, Kerry L LaPlante

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Statins, Allies against Antibiotic Resistance?Current medicinal chemistry · 2025
    Review
  5. Review
  6. Unveiling the Antibacterial Properties of Statins: AnAdvances in pharmacological and pharmaceutical sciences · 2024
    Article
  7. Review
  8. Innovations in Evaluating Statin Benefit and Efficacy inInternational journal of molecular sciences · 2022
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Pathogen Lists Do Not Tell Us What We Need to Do.The American journal of tropical medicine and hygiene · 2019
    Article
  18. Observational
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Aisling R CaffreyVeterans Affairs Medical Center, Infectious Diseases Research Program and Center of Innovation in Long Term Services and Supports, Providence, Rhode Island, USA Aisling_Caffrey@uri.edu KerryLaPlante@uri.edu.
Tristan T TimbrookVeterans Affairs Medical Center, Infectious Diseases Research Program and Center of Innovation in Long Term Services and Supports, Providence, Rhode Island, USA.
Eunsun NohUniversity of Rhode Island College of Pharmacy, Kingston, Rhode Island, USA.
George SakoulasUniversity of California San Diego School of Medicine, La Jolla, California, USA.
Steven M OpalInfectious Disease Division, Memorial Hospital of Rhode Island, Providence, Rhode Island, USA.
Victor NizetUniversity of California San Diego School of Medicine, La Jolla, California, USA.
Kerry L LaPlanteVeterans Affairs Medical Center, Infectious Diseases Research Program and Center of Innovation in Long Term Services and Supports, Providence, Rhode Island, USA Aisling_Caffrey@uri.edu KerryLaPlante@uri.edu.
University of Rhode Island · USUniversity of California, San Diego · USBrown University · USProvidence College · US

Funding

Safety and Dose Optimization of High-Dose Anakinra in Kawasaki DiseaseU54HD090259 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CAPPARELLI, EDMUND VINCENT, NIZET, VICTOR · 2016 to 2018
$2.2M
NICHD NIH HHS U54 HD090259
6 · The paper itself

Abstract

In addition to cholesterol-lowering capabilities, statins possess anti-inflammatory and immunomodulatory effects. We sought to quantify the real-world impact of different statin exposure patterns on clinical outcomes in

Indexed as

AgedAnti-Bacterial AgentsBacteremiaDrug CombinationsDrug SynergismFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedPropensity ScoreProportional Hazards ModelsRetrospective StudiesStaphylococcal InfectionsTreatment OutcomeAnti-Bacterial AgentsDrug CombinationsHydroxymethylglutaryl-CoA Reductase Inhibitorsanti-inflammatory and immunomodulatory effectsbacteremiaHMG-CoA reductase inhibitorsmortalityStaphylococcus aureusstatins

Identifiers

PMID28069650
PMCPMC5328562
OpenAlexW2568427041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.