Evidence map›Paper›PMID 28069647›Full record

ArticleAntimicrobial agents and chemotherapy2017

Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila.

Ghislaine Descours, Christophe Ginevra, Nathalie Jacotin, Françoise Forey, Joëlle Chastang, Elisabeth Kay, Jerome Etienne, Gérard Lina, Patricia Doublet, Sophie Jarraud

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Antibiotic Resistance ofInternational journal of environmental research and public health · 2020
    Pooled it
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  6. Antibiotic susceptibility situation of environmentalJournal of water and health · 2024
    Article
  7. Quantitative Microbial Risk Assessment of Antibiotic-ResistantEnvironmental science & technology · 2024
    Article
  8. Assessment of macrolide susceptibility ofNorthern clinics of Istanbul · 2024
    Article
  9. Development of heat-shock resistance inApplied and environmental microbiology · 2023
    Article
  10. Article
  11. Antibiotic susceptibility pattern of Portuguese environmental Legionella isolates.Frontiers in cellular and infection microbiology · 2023
    Article
  12. Bacterial persistence inFrontiers in cellular and infection microbiology · 2023
    Article
  13. Proteome Exploration ofMicrobiology spectrum · 2022
    Article
  14. Review
  15. Molecular Mechanism ofInfection and drug resistance · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Ghislaine DescoursCIRI, Centre International de Recherche en Infectiologie, Equipe Pathogénèse des Légionelles, Lyon, France ghislaine.descours@univ-lyon1.fr.
Christophe GinevraCIRI, Centre International de Recherche en Infectiologie, Equipe Pathogénèse des Légionelles, Lyon, France.
Nathalie JacotinHospices Civils de Lyon, Groupement Hospitalier Nord, National Reference Centre of Legionella, Institute for Infectious Agents, Lyon, France.
Françoise ForeyHospices Civils de Lyon, Groupement Hospitalier Nord, National Reference Centre of Legionella, Institute for Infectious Agents, Lyon, France.
Joëlle ChastangHospices Civils de Lyon, Groupement Hospitalier Nord, National Reference Centre of Legionella, Institute for Infectious Agents, Lyon, France.
Elisabeth KayCIRI, Centre International de Recherche en Infectiologie, Equipe Pathogénèse des Légionelles, Lyon, France.
Jerome EtienneInserm, U1111, Université Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, Lyon, France.
Gérard LinaInserm, U1111, Université Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, Lyon, France.
Patricia DoubletCIRI, Centre International de Recherche en Infectiologie, Equipe Pathogénèse des Légionelles, Lyon, France.
Sophie JarraudCIRI, Centre International de Recherche en Infectiologie, Equipe Pathogénèse des Légionelles, Lyon, France.
Hospices Civils de Lyon · FRCentre National de la Recherche Scientifique · FRCentre International de Recherche en Infectiologie · FRÉcole Normale Supérieure de Lyon · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monitoring the emergence of antibiotic resistance is a recent issue in the treatment of Legionnaires' disease. Macrolides are recommended as first-line therapy, but resistance mechanisms have not been studied in

Indexed as

MutationAnti-Bacterial AgentsAzithromycinBacterial ProteinsClone CellsDrug Resistance, BacterialErythromycinHigh-Throughput Nucleotide SequencingLegionella pneumophilaMicrobial Sensitivity TestsProtein IsoformsRibosomal ProteinsRNA, Ribosomal, 23SAnti-Bacterial AgentsAzithromycinBacterial ProteinsErythromycinProtein IsoformsRibosomal ProteinsRNA, Ribosomal, 23S23S rRNALegionella pneumophilamacrolideresistanceribosomal mutationsribosomal proteins

Identifiers

PMID28069647
PMCPMC5328525
OpenAlexW2567733104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.