Evidence map›Paper›PMID 28069446›Full record

ArticleInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2017

RICH2 is implicated in viraemic control of HIV-1 in black South African individuals.

Maria Paximadis, Refilwe N Ngqobe, Richard E Chaisson, Neil A Martinson, Caroline T Tiemessen

Abstract read
In one paragraph

Article in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria PaximadisNational Institute for Communicable Diseases, Centre for HIV and STIs, Cell Biology, Johannesburg, South Africa; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Electronic address: paxim@nicd.ac.za.
Refilwe N NgqobeNational Institute for Communicable Diseases, Centre for HIV and STIs, Cell Biology, Johannesburg, South Africa.
Richard E ChaissonJohns Hopkins University Center for AIDS Research, Baltimore, MD, USA.
Neil A MartinsonPerinatal HIV Research Unit (PHRU), University of the Witwatersrand, Johannesburg, South Africa; MRC Soweto Matlosana Centre for HIV/AIDS and TB Research, South Africa.
Caroline T TiemessenNational Institute for Communicable Diseases, Centre for HIV and STIs, Cell Biology, Johannesburg, South Africa; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Longitudinal Study of HIV-Associated Lung Infections in SowetoR01HL090312 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CHAISSON, RICHARD E. · 2007 to 2012
$3.3M
NHLBI NIH HHS R01 HL090312NIAID NIH HHS P30 AI094189
6 · The paper itself

Abstract

An intronic single nucleotide polymorphism (SNP) in RICH2 (rs2072255; 255

Indexed as

AdultAllelesAlternative SplicingBlack PeopleCase-Control StudiesCD4 Lymphocyte CountCD4-Positive T-LymphocytesDisease ProgressionDisease ResistanceFemaleGene Expression RegulationGTPase-Activating ProteinsHIV-1HIV InfectionsHumansLinkage DisequilibriumARHGAP44 protein, humanGTPase-Activating ProteinsNF-kappa BRNA, ViralHIV-1Host genesNatural controlRICH2Tetherin

Identifiers

PMID28069446
PMCPMC5330811

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.