ArticleRadiation oncology (London, England)2017
Influence of daily imaging on plan quality and normal tissue toxicity for prostate cancer radiotherapy.
Article in Radiation oncology (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Refining imaging parameters for dual-energy cone-beam computed tomography in image-guided radiation therapy.Journal of applied clinical medical physics · 2026Article
- A methodological design and an empirical study for assessing the maturity of an UASR based on the AHP-EWM and the FSEM fusion model.Scientific reports · 2025Article
- [Quantitative evaluation of radiotherapy plan in precise external beam radiotherapy process management for cervical cancer].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
- Feasibility and guidelines for the use of an injectable fiducial marker (BioXmarkF1000Research · 2023Article
- Evaluation of a new acrylic-lead shielding device for peripheral dose reduction during cone-beam computed tomography.BJR open · 2022Article
- Adaptive radiotherapy and the dosimetric impact of inter- and intrafractional motion on the planning target volume for prostate cancer patients.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020Article
- Evaluation of a Novel Liquid Fiducial Marker, BioXmarkCancers · 2020Article
- Image guidance and positioning accuracy in clinical practice: influence of positioning errors and imaging dose on the real dose distribution for head and neck cancer treatment.Radiation oncology (London, England) · 2018Article
- Imaging dose and secondary cancer risk in image-guided radiotherapy of pediatric patients.Radiation oncology (London, England) · 2018Article
- Shorter treatment times reduce the impact of intra-fractional motion : A real-time 4DUS study comparing VMAT vs. step-and-shoot IMRT for prostate cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2018Article
- Evaluation of IGRT-Induced Imaging Doses and Secondary Cancer Risk for SBRT Early Lung Cancer Patients In Silico Study.Technology in cancer research & treatmentArticle
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5 authors.
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Abstract
backgroundModern radiotherapy offers various possibilities for image guided verification of patient positioning. Different clinically relevant IGRT (image guided radiotherapy) scenarios were considered with regard to their influence on dosimetric plan quality and normal tissue complication probability (NTCP).
methodsThis study is based on treatment plans of 50 prostate patients. We evaluate the clinically performed IGRT and simulate the influence of different daily IGRT scenarios on plan quality. Imaging doses of planar and cone-beam-CT (CBCT) images for three different energies (6 MV, 1 MV and 121 kV) were added to the treatment plans. The plan quality of the different scenarios was assessed by a visual inspection of the dose distribution and dose-volume-histogram (DVH) and a statistical analysis of DVH criteria. In addition, an assessment of the normal tissue complication probability was performed.
resultsDaily 1MV-CBCTs result in undesirable high dose regions in the target volume. The DVH shows that the scenarios with actual imaging performed, daily kV-CBCT and daily 6MV imaging (1x CBCT, 4x planar images per week) do not differ exceedingly from the original plan; especially imaging with daily kV-CBCT has little influence to the sparing of organs at risk. In contrast, daily 1MV- CBCT entails an additional dose of up to two fraction doses. Due to the additional dose amount some DVH constraints for plan acceptability could no longer be satisfied, especially for the daily 1MV-CBCT scenario. This scenario also shows increased NTCP for the rectum.
conclusionDaily kV-CBCT has negligible influence on plan quality and is commendable for the clinical routine. If no kV-modality is available, a daily IGRT scenario with one CBCT per week and planar axial images on the other days should be preferred over daily MV-CBCT.
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