Observational studyBMC ophthalmology2017
Corneal hysteresis in patients with glaucoma-like optic discs, ocular hypertension and glaucoma.
Observational study in BMC ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Cornea biomechanics and biometric evaluations in immunoglobulin G4-related ophthalmic disease.PloS one · 2026Article
- Axial Length to Corneal Radius of Curvature Ratio (AL/CR) and Refractive Errors in a Single Center Romanian Population.Biomedicines · 2025Article
- Polygenic risk score-based phenome-wide association for glaucoma and its impact on disease susceptibility in two large biobanks.Journal of translational medicine · 2024Article
- In vivo assessment of the ocular biomechanical properties in patients with idiopathic normal pressure hydrocephalus.International ophthalmology · 2024Article
- Particular Anatomy of the Hyperopic Eye and Potential Clinical Implications.Medicina (Kaunas, Lithuania) · 2023Article
- Relationship between Inter-Eye Asymmetries in Corneal Hysteresis and Visual Field Severity in Patients with Primary Open-Angle Glaucoma.Journal of clinical medicine · 2023Article
- Evaluation of corneal hysteresis after pars plana vitrectomy combined phacoemulsification and intraocular lens implantation.Scientific reports · 2022Article
- Corneal Biomechanics for Ocular Hypertension, Primary Open-Angle Glaucoma, and Amyloidotic Glaucoma: A Comparative Study by Corvis ST.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Corneal Biomechanical Parameters and Central Corneal Thickness in Glaucoma Patients, Glaucoma Suspects, and a Healthy Population.Journal of clinical medicine · 2021Article
- Article
- The Relationship Between Corneal Hysteresis and Retinal Ganglion Cells - A Step Forward in Early Glaucoma Diagnosis.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Effects of vitamin D deficiency on intraocular pressure values obtained by ocular response analyzer.International ophthalmology · 2020Article
- Corneal Hysteresis as a Biomarker of Glaucoma: Current Insights.Clinical ophthalmology (Auckland, N.Z.) · 2020Review
- Corneal Buckling during Applanation and Its Effect on the Air Pressure Curve in Ocular Response Analyzer.International journal of environmental research and public health · 2019Article
- Relationship between the biomechanical properties of the cornea and anterior segment measurements.Clinics (Sao Paulo, Brazil) · 2018Article
- Relationships between corneal biomechanics and the structural and functional parameters of glaucoma damage.Arquivos brasileiros de oftalmologiaObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo compare corneal hysteresis (CH) measurements between patients with glaucoma, ocular hypertension (OHT) and glaucoma-like optic discs (GLD)- defined as a cup to disc ratio greater than or equal to 0.6 with normal intraocular pressure (IOP) and visual fields. The secondary aim was to investigate whether corneal resistance factor (CRF) and central corneal thickness (CCT) differ between patient groups.
methodsIn this cross sectional study a total of 123 patients (one eye each) were recruited from a glaucoma outpatient department to undergo ocular response analyser (ORA) testing and ultrasound pachymetry as well as clinical examination. A One-way Analysis of Covariance (ANCOVA) was conducted to evaluate the mean difference in CH between the three diagnostic groups (glaucoma, OHT and GLD) correcting for potential confounding factors, IOP and age. Analysis was repeated for CRF and CCT.
resultsThere was a significant difference in mean CH across the three diagnosis groups; F(2, 115) = 96.95; p < 0.001. Mean CH significantly higher for GLD compared to glaucoma (mean difference 1.83, p < 0.001), and significantly higher for OHT compared to glaucoma (mean difference 2.35, p < 0.001). Mean CH was slightly lower in patients with GLD than those with OHT but this difference was not statistically significant. A similar pattern was seen when the analysis was repeated for CRF and CCT.
conclusionsHigher CH in GLD and OHT compared to glaucoma suggests increased viscoelasticity of ocular tissues may have a protective role against glaucoma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.