ArticleBMC cancer2017
Early life socioeconomic environment and mammographic breast density.
Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed.
- Socioeconomic Status at Birth and Breast Tissue Composition in Adolescence and Adulthood.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- Exposure to natural vegetation in relation to mammographic density in a Massachusetts-based clinical cohort.Environmental epidemiology (Philadelphia, Pa.) · 2022Article
- The epidemiologic factors associated with breast density: A review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022Review
- A vision for exposome epidemiology: The pregnancy exposome in relation to breast cancer in the Child Health and Development Studies.Reproductive toxicology (Elmsford, N.Y.) · 2020Article
- Prepubertal and Pubertal Endocrine-Disrupting Chemical Exposure and Breast Density among Chilean Adolescents.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018Article
- Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls.Epigenetics · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundEarly life social environment may influence breast cancer through shaping risk factors operating in early life, adolescence and adulthood, or may be associated with breast cancer risk independent of known risk factors. We investigated the associations between early life socioeconomic status (SES) and mammographic density, a strong risk factor for breast cancer, and the extent to which these associations were independent of risk factors across the lifecourse.
methodsWe used data from an adult follow-up study of two U.S. birth cohorts of women (average age = 43 years) with prospectively collected data starting during the pregnancy of the mother and continuing through early childhood of the offspring. We collected data on factors in later life periods through computer-assisted interviews with the offspring as adults, and obtained routine clinical mammograms for measurement of percent density and dense and nondense breast areas using a computer assisted method. We used generalized estimating equation models for multivariable analysis to account for correlated data for sibling sets within the study sample (n = 700 composed of 441 individuals and 127 sibling sets).
resultsHighest vs. lowest family income level around the time of birth was associated with smaller dense breast area after adjustment for early life factors (e.g., birthweight, maternal smoking during pregnancy) and risk factors in later life periods, including adult body mass index (BMI) and adult SES (β = -8.2 cm
conclusionsWe did not observe consistent associations between different measures of early life SES and mammographic density in adulthood.
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