Evidence map›Paper›PMID 28068309›Full record

ArticleNature chemical biology2017

Biomimetic spinning of artificial spider silk from a chimeric minispidroin.

Marlene Andersson, Qiupin Jia, Ana Abella, Xiau-Yeen Lee, Michael Landreh, Pasi Purhonen, Hans Hebert, Maria Tenje, Carol V Robinson, Qing Meng and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed.

  1. Article
  2. Liquid-liquid phase separation enables chromatography-free purification and high-performance spidroin-amyloid hybrid silk fibers.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
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  6. Article
  7. Review
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  11. Article
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  13. Article
  14. In the flow, how fluid dynamics shapes amyloid formation.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marlene AnderssonDepartment of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Qiupin JiaInstitute of Biological Sciences and Biotechnology, Donghua University, Shanghai, P.R. China.
Ana AbellaETSI de Caminos and Center for Biomedical Technology, Universidad Politécnica de Madrid, Madrid, Spain.
Xiau-Yeen LeeETSI de Caminos and Center for Biomedical Technology, Universidad Politécnica de Madrid, Madrid, Spain.
Michael LandrehDepartment of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, Oxford, UK.
Pasi PurhonenDepartment of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
Hans HebertDepartment of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
Maria TenjeDepartment of Engineering Sciences, SciLifeLab, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-1264-1337
Carol V RobinsonDepartment of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, Oxford, UK.
Qing MengInstitute of Biological Sciences and Biotechnology, Donghua University, Shanghai, P.R. China.
Gustavo R PlazaETSI de Caminos and Center for Biomedical Technology, Universidad Politécnica de Madrid, Madrid, Spain.
Jan JohanssonDepartment of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Anna RisingDepartment of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.ORCID 0000-0002-1872-1207

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein we present a chimeric recombinant spider silk protein (spidroin) whose aqueous solubility equals that of native spider silk dope and a spinning device that is based solely on aqueous buffers, shear forces and lowered pH. The process recapitulates the complex molecular mechanisms that dictate native spider silk spinning and is highly efficient; spidroin from one liter of bacterial shake-flask culture is enough to spin a kilometer of the hitherto toughest as-spun artificial spider silk fiber.

Indexed as

BiomimeticsAnimalsFibroinsHydrogen-Ion ConcentrationRecombinant ProteinsFibroinsRecombinant Proteins

Identifiers

PMID28068309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.