Evidence map›Paper›PMID 28068220›Full record

ArticleeLife2017

Metabolite exchange between microbiome members produces compounds that influence

Caleb N Fischer, Eric P Trautman, Jason M Crawford, Eric V Stabb, Jo Handelsman, Nichole A Broderick

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Meta-analysis of Diets Used inG3 (Bethesda, Md.) · 2020
    Pooled it
  2. Article
  3. Article
  4. Gut microbiome of the grape berry moth,Microbial genomics · 2026
    Article
  5. A defined community of core gut microbiota members promotes cognitive performance in honey bees.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Insects · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Is it time to assignApplied and environmental microbiology · 2025
    Article
  14. Environment and diet shape the geography-specificApplied and environmental microbiology · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Infection and immunity · 2025
    Review
  20. Article

45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caleb N FischerDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States.ORCID 0000-0003-4223-8511
Eric P TrautmanDepartment of Chemistry, Yale University, New Haven, United States.
Jason M CrawfordDepartment of Chemistry, Yale University, New Haven, United States.ORCID 0000-0002-7583-1242
Eric V StabbDepartment of Microbiology, University of Georgia, Athens, United States.
Jo HandelsmanDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States.
Nichole A BroderickDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States.ORCID 0000-0002-6830-9456

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007499 · NIGMS · YALE UNIVERSITY · PI CARLSON, JOHN R, REINKE, VALERIE J · 1985 to 2022
$13.9M
Training in Genomics and Proteomics TechnologiesT32HG003198 · NHGRI · YALE UNIVERSITY · PI BREAKER, RONALD R · 2004 to 2015
$4.9M
Invasion and Exclusion by Enterococcus faecalis in the Manduca gut communityR01GM099563 · NIGMS · YALE UNIVERSITY · PI BREAKER, RONALD R, DUNNY, GARY M · 2013 to 2016
$1.1M
Metagenetic analysis of microbial community behaviorRC1DK086831 · NIDDK · YALE UNIVERSITY · PI HANDELSMAN, JO E. · 2009 to 2010
$964k
NCATS NIH HHS UL1 TR001863NHGRI NIH HHS T32 HG003198NIDDK NIH HHS RC1 DK086831NIGMS NIH HHS R01 GM099563NIGMS NIH HHS T32 GM007499
6 · The paper itself

Abstract

Animals host multi-species microbial communities (microbiomes) whose properties may result from inter-species interactions; however, current understanding of host-microbiome interactions derives mostly from studies in which elucidation of microbe-microbe interactions is difficult. In exploring how

Indexed as

MicrobiotaAcetic AcidAcetobacterAnimalsBehavior, AnimalDrosophila melanogasterEthanolSaccharomycesVolatile Organic CompoundsAcetic AcidEthanolVolatile Organic CompoundsD. melanogasterecologyhost-microbe interactionsinfectious diseasemetabolismmicrobe-microbe interactionsmicrobiologymicrobiotaolfactionS. cerevisiae

Identifiers

PMID28068220
PMCPMC5222558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.