Evidence map›Paper›PMID 28068078›Full record

ArticleACS nano2017

Enriching Nanoparticles via Acoustofluidics.

Zhangming Mao, Peng Li, Mengxi Wu, Hunter Bachman, Nicolas Mesyngier, Xiasheng Guo, Sheng Liu, Francesco Costanzo, Tony Jun Huang

Erratum issuedAbstract read
In one paragraph

Article in ACS nano, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Review
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  12. Quantitative Acoustophoresis.ACS nanoscience Au · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Sonoporation: Past, Present, and Future.Advanced materials technologies · 2022
    Article
  17. Article
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  19. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Zhangming MaoDepartment of Engineering Science and Mechanics, The Pennsylvania State University , University Park, Pennsylvania 16802, United States.
Peng LiC. Eugene Bennett Department of Chemistry, West Virginia University , Morgantown, West Virginia 26506, United States.
Mengxi WuDepartment of Engineering Science and Mechanics, The Pennsylvania State University , University Park, Pennsylvania 16802, United States.
Hunter BachmanDepartment of Mechanical Engineering and Material Science, Duke University , Durham, North Carolina 27708, United States.
Nicolas MesyngierDepartment of Engineering Science and Mechanics, The Pennsylvania State University , University Park, Pennsylvania 16802, United States.
Xiasheng GuoKey Laboratory of Modern Acoustics (MOE), Department of Physics, Collaborative Innovation Center of Advanced Microstructure, Nanjing University , Nanjing 210093, China.
Sheng LiuSchool of Power and Mechanical Engineering, Wuhan University , Wuhan 430072, China.
Francesco CostanzoDepartment of Engineering Science and Mechanics, The Pennsylvania State University , University Park, Pennsylvania 16802, United States.
Tony Jun HuangDepartment of Engineering Science and Mechanics, The Pennsylvania State University , University Park, Pennsylvania 16802, United States.ORCID 0000-0003-1205-3313

Funding

Extracellular vesicles and their ncRNA cargo as markers of trophoblast injuryR01HD086325 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SADOVSKY, YOEL · 2015 to 2019
$3.6M
NICHD NIH HHS R01 HD086325
6 · The paper itself

Abstract

Focusing and enriching submicrometer and nanometer scale objects is of great importance for many applications in biology, chemistry, engineering, and medicine. Here, we present an acoustofluidic chip that can generate single vortex acoustic streaming inside a glass capillary through using low-power acoustic waves (only 5 V is required). The single vortex acoustic streaming that is generated, in conjunction with the acoustic radiation force, is able to enrich submicrometer- and nanometer-sized particles in a small volume. Numerical simulations were used to elucidate the mechanism of the single vortex formation and were verified experimentally, demonstrating the focusing of silica and polystyrene particles ranging in diameter from 80 to 500 nm. Moreover, the acoustofluidic chip was used to conduct an immunoassay in which nanoparticles that captured fluorescently labeled biomarkers were concentrated to enhance the emitted signal. With its advantages in simplicity, functionality, and power consumption, the acoustofluidic chip we present here is promising for many point-of-care applications.

Indexed as

Microfluidic Analytical TechniquesBiomarkersFluorescenceNanoparticlesPoint-of-Care SystemsPolystyrenesSoundBiomarkersPolystyrenesacoustic streamingacoustic tweezersacoustofluidicsnanoparticle enrichmentsurface acoustic waves

Identifiers

PMID28068078
PMCPMC5536981

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.