ArticleInternational journal of environmental research and public health2017
The Effects of Age, Period, and Cohort on Mortality from Ischemic Heart Disease in China.
Article in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990-2019): an age-period-cohort analysis of the global burden of disease study 2019.Frontiers in cardiovascular medicine · 2024Article
- Tranilast reduces cardiomyocyte injury induced by ischemia‑reperfusion via Nrf2/HO‑1/NF‑κB signaling.Experimental and therapeutic medicine · 2023Article
- A likelihood ratio test on temporal trends in age-period-cohort models with applications to the disparities of heart disease mortality among US populations and comparison with Japan.Statistics in medicine · 2021Article
- Trends in Cardiovascular Disease Morbidity and Mortality in American Indians Over 25 Years: The Strong Heart Study.Journal of the American Heart Association · 2019Article
- Historical trends in suicide risk for the residents of mainland China: APC modeling of the archived national suicide mortality rates during 1987-2012.Social psychiatry and psychiatric epidemiology · 2019Article
- Meta-Analysis ofToxics · 2018Article
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Authors and funding
4 authors.
Funding
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Abstract
In contrast with most developed countries, mortality due to ischemic heart disease (IHD) continues to rise in China. We examined the effects of age, period, and cohort on IHD mortality in urban and rural populations from 1987 to 2013 to identify the drivers of this trend. Region-specific data on annual IHD mortality among adults aged 20 to 84 years and corresponding population statistics were collected. We then tested for age, period, and cohort effects using the Intrinsic Estimator approach. Our results indicated that IHD mortality in China increased significantly over the three decades studied. There was a log-linear increase in the age effect on IHD mortality as those aged 80-84 showed 277 and 161 times greater IHD mortality risk than those aged 20-24 in urban and rural populations, respectively. While there was an upward trend in the period effect in both populations, the influence of the cohort effect on mortality decreased over time for those born from 1904 to 1993. The age, period, and cohort effects on mortality in China were generally comparable between urban and rural populations. The results suggest that population aging is a major driver behind the rapid rise in IHD mortality. Increased exposure to air pollution may also have played a role in driving the period effect.
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