Evidence map›Paper›PMID 28067841›Full record

ArticleMolecules (Basel, Switzerland)2017

Lectin Digestibility and Stability of Elderberry Antioxidants to Heat Treatment In Vitro.

Pilar Jiménez, Patricia Cabrero, Damian Cordoba-Diaz, Manuel Cordoba-Diaz, Manuel Garrosa, Tomás Girbés

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Effects of Heat Treatment on Physicochemical Properties ofInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. GenusInternational journal of molecular sciences · 2024
    Review
  5. Fruits of Wild-Grown Shrubs for Health Nutrition.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Bioactive properties ofJournal of functional foods · 2018
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pilar JiménezNutrición y Bromatología, Facultad de Medicina, Universidad de Valladolid, Valladolid 47005, Spain. pilarj@bio.uva.es.
Patricia CabreroNutrición y Bromatología, Facultad de Medicina, Universidad de Valladolid, Valladolid 47005, Spain. patricia_cabrero@hotmail.com.
Damian Cordoba-DiazFarmacia y Tecnología Farmacéutica, Facultad de Farmacia and Instituto Universitario de Farmacia Industrial (IUFI), Universidad Complutense de Madrid, Madrid 28040, Spain. damianco@farm.ucm.es.
Manuel Cordoba-DiazFarmacia y Tecnología Farmacéutica, Facultad de Farmacia and Instituto Universitario de Farmacia Industrial (IUFI), Universidad Complutense de Madrid, Madrid 28040, Spain. mcordoba@farm.ucm.es.
Manuel GarrosaBiología Celular, Histología y Farmacología, Facultad de Medicina and Instituto de Neurociencias de Castilla y León (INCYL), Universidad de Valladolid, Valladolid 47005, Spain. garrosa@med.uva.es.
Tomás GirbésNutrición y Bromatología, Facultad de Medicina, Universidad de Valladolid, Valladolid 47005, Spain. girbes@bio.uva.es.
Universidad de Valladolid · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elderberry contains healthy low molecular weight nutraceuticals and lectins which are sequence-related to the elderberry allergen Sam n1. Some of these lectins are type II ribosome-inactivating proteins. The sensitivity of native lectins present in elderberry fruits and bark to the proteolysis triggered by in vitro simulated gastric and duodenal fluids has been investigated. It was found that these lectins are refractory to proteolysis. Nonetheless, incubation for 5-10 min in a boiling water bath completely sensitized them to the hydrolytic enzymes in vitro. Under these conditions neither total Folin-Ciocalteau's reagent reactive compounds, total anthocyanins and the mixture of cyanidin-3-glucoside plus cyanidin-3-sambubioside, nor antioxidant and free-radical scavenging activities were affected by more than 10% for incubations of up to 20 min. Therefore, short-time heat treatment reduces potential allergy-related risks deriving from elderberry consumption without seriously affecting its properties as an antioxidant and free-radical scavenging food.

Indexed as

AllergensAntioxidantsFruitHot TemperaturePepsin APlant BarkPlant ExtractsPlant LectinsPlants, MedicinalProtein StabilityProteolysisRibosome Inactivating Proteins, Type 2Sambucus nigraSpainAllergensAntioxidantsPepsin APlant ExtractsPlant LectinsRibosome Inactivating Proteins, Type 2elderberryfree-radicalslectinpolyphenolribosome-inactivating proteinSambucus nigra

Identifiers

PMID28067841
PMCPMC6155927
OpenAlexW2569462596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.