ArticleInternational journal of molecular sciences2017
The Cause of Death of a Child in the 18th Century Solved by Bone Microbiome Typing Using Laser Microdissection and Next Generation Sequencing.
Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- The Future Is Now: Unraveling the Expanding Potential of Human (Necro)Microbiome in Forensic Investigations.Microorganisms · 2023Review
- Could health only be defined by an equilibrated microbiome? A COVID-19 reappraisal.Ethics, medicine, and public health · 2021Article
- Microbiome Influence in the Pathogenesis of Prion and Alzheimer's Diseases.International journal of molecular sciences · 2019Review
- The Prenatal Microbiome: A New Player for Human Health.High-throughput · 2018Review
- The High-Throughput Analyses Era: Are We Ready for the Data Struggle?High-throughput · 2018Article
- Human Microbiome Acquisition and Bioinformatic Challenges in Metagenomic Studies.International journal of molecular sciences · 2018Review
- A common microbial signature is present in the lower airways of interstitial lung diseases including sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2018Article
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The history of medicine abounds in cases of mysterious deaths, especially by infectious diseases, which were probably unresolved because of the lack of knowledge and of appropriate technology. The aim of this study was to exploit contemporary technologies to try to identify the cause of death of a young boy who died from a putative "infection" at the end of the 18th century, and for whom an extraordinarily well-preserved minute bone fragment was available. After confirming the nature of the sample, we used laser microdissection to select the most "informative" area to be examined. Tissue genotyping indicated male gender, thereby confirming the notary's report. 16S ribosomal RNA sequencing showed that
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Registered trials
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