Evidence map›Paper›PMID 28067317›Full record

ArticleScientific reports2017

Glucose-6-Phosphate Isomerase (G6PI) Mediates Hypoxia-Induced Angiogenesis in Rheumatoid Arthritis.

Ying Lu, Shan-Shan Yu, Ming Zong, Sha-Sha Fan, Tian-Bao Lu, Ru-Han Gong, Li-Shan Sun, Lie-Ying Fan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Microorganisms · 2026
    Article
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  7. Article
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  12. Targeting glycolytic pathway in fibroblast-like synoviocytes for rheumatoid arthritis therapy: challenges and opportunities.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Metabolites as drivers and targets in rheumatoid arthritis.Clinical and experimental immunology · 2022
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ying LuDepartment of Clinical Laboratory, Shanghai East Hospital, School of Medicine, Tongji University, 150 Ji Mo Road, Shanghai 200120, People's Republic of China.
Shan-Shan YuDepartment of Clinical Laboratory, Shanghai East Hospital, School of Medicine, Tongji University, 150 Ji Mo Road, Shanghai 200120, People's Republic of China.
Ming ZongDepartment of Clinical Laboratory, Shanghai East Hospital, School of Medicine, Tongji University, 150 Ji Mo Road, Shanghai 200120, People's Republic of China.
Sha-Sha FanDepartment of Clinical Laboratory, Shanghai East Hospital, School of Medicine, Tongji University, 150 Ji Mo Road, Shanghai 200120, People's Republic of China.
Tian-Bao LuDepartment of Clinical Laboratory, Shanghai East Hospital, School of Medicine, Tongji University, 150 Ji Mo Road, Shanghai 200120, People's Republic of China.
Ru-Han GongDepartment of Clinical Laboratory, Shanghai East Hospital, School of Medicine, Tongji University, 150 Ji Mo Road, Shanghai 200120, People's Republic of China.
Li-Shan SunDepartment of Clinical Laboratory, Shanghai East Hospital, School of Medicine, Tongji University, 150 Ji Mo Road, Shanghai 200120, People's Republic of China.
Lie-Ying FanDepartment of Clinical Laboratory, Shanghai East Hospital, School of Medicine, Tongji University, 150 Ji Mo Road, Shanghai 200120, People's Republic of China.
Shanghai East Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The higher level of Glucose-6-phosphate isomerase (G6PI) has been found in both synovial tissue and synovial fluid of rheumatoid arthritis (RA) patients, while the function of G6PI in RA remains unclear. Herein we found the enrichment of G6PI in microvascular endothelial cells of synovial tissue in RA patients, where a 3% O

Indexed as

Arthritis, RheumatoidCell CycleCell HypoxiaCell MovementCell ProliferationCells, CulturedCytokinesEndothelial CellsGlucose-6-Phosphate IsomeraseHumansHypoxiaHypoxia-Inducible Factor 1, alpha SubunitJoint CapsuleNeovascularization, PathologicVascular Endothelial Growth Factor ACytokinesGlucose-6-Phosphate IsomeraseGPI protein, humanHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitVascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID28067317
PMCPMC5220294
OpenAlexW2569892382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.