Evidence map›Paper›PMID 28067304›Full record

ArticleScientific reports2017

Weissella cibaria WIKIM28 ameliorates atopic dermatitis-like skin lesions by inducing tolerogenic dendritic cells and regulatory T cells in BALB/c mice.

Seul Ki Lim, Min-Sung Kwon, Jieun Lee, Young Joon Oh, Ja-Young Jang, Jong-Hee Lee, Hae Woong Park, Young-Do Nam, Myung-Ji Seo, Seong Woon Roh and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 93 citations in OpenAlex.

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  10. Oral administration ofFrontiers in microbiology · 2025
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  11. Exploring the Metabolic Effects of a Herbal Remedy ofAntioxidants (Basel, Switzerland) · 2024
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  13. Foods (Basel, Switzerland) · 2024
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  15. Microbiological effect of topically appliedFrontiers in veterinary science · 2024
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  16. Description and Genomic Characteristics ofJournal of microbiology and biotechnology · 2023
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  19. TheFrontiers in microbiology · 2023
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  20. Frontiers in microbiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Seul Ki LimMicrobiology and Functionality Research Group, World Institute of Kimchi, Gwangju 61755, Republic of Korea.
Min-Sung KwonMicrobiology and Functionality Research Group, World Institute of Kimchi, Gwangju 61755, Republic of Korea.
Jieun LeeMicrobiology and Functionality Research Group, World Institute of Kimchi, Gwangju 61755, Republic of Korea.
Young Joon OhMicrobiology and Functionality Research Group, World Institute of Kimchi, Gwangju 61755, Republic of Korea.
Ja-Young JangMicrobiology and Functionality Research Group, World Institute of Kimchi, Gwangju 61755, Republic of Korea.
Jong-Hee LeeMicrobiology and Functionality Research Group, World Institute of Kimchi, Gwangju 61755, Republic of Korea.
Hae Woong ParkAdvanced Process Technology and Fermentation Research Group, World Institute of Kimchi, Gwangju 61755, Republic of Korea.
Young-Do NamResearch Group of Gut Microbiome, Korea Food Research Institute, Seongnam 13539, Republic of Korea.
Myung-Ji SeoDivision of Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.
Seong Woon RohBiological Disaster Analysis Group, Korea Basic Science Institute, Daejeon 34133, Republic of Korea.
Hak-Jong ChoiMicrobiology and Functionality Research Group, World Institute of Kimchi, Gwangju 61755, Republic of Korea.
World Institute of Kimchi · KRIncheon National University · KRInstitute of World Economics · HUKorea Basic Science Institute · KRKorea Food Research Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The occurrence of atopic dermatitis (AD), a chronic inflammatory skin disease, has been increasing steadily in children and adults in recent decades. In this study, we evaluated the ability of the lactic acid bacterium Weissella cibaria WIKIM28 isolated from gatkimchi, a Korean fermented vegetable preparation made from mustard leaves, to suppress the development of AD induced by 2,4-dinitrochlorobenzene in a murine model. Oral administration of W. cibaria WIKIM28 reduced AD-like skin lesions, epidermal thickening, and serum immunoglobulin E levels. Furthermore, the production of type 2 helper T (Th2) cytokines such as interleukin (IL)-4, IL-5, and IL-13 decreased in peripheral lymph node cells. Moreover, the intake of W. cibaria WIKIM28 increased the proportion of CD4

Indexed as

Immune ToleranceAdministration, OralAnimalsBacterial ProteinsDendritic CellsDermatitis, AtopicDisease Models, AnimalImmunoglobulin EImmunologic FactorsMice, Inbred BALB CSkinT-Lymphocytes, RegulatoryTreatment OutcomeWeissellaBacterial ProteinsImmunoglobulin EImmunologic Factors

Identifiers

PMID28067304
PMCPMC5220369
OpenAlexW2570527903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.