Evidence map›Paper›PMID 28067122›Full record

ArticleStatistical methods in medical research2018

Mediation analysis for count and zero-inflated count data.

Jing Cheng, Nancy F Cheng, Zijian Guo, Steven Gregorich, Amid I Ismail, Stuart A Gansky

Abstract read
In one paragraph

Article in Statistical methods in medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Motivational Interviewing and Childhood Caries: A Randomised Controlled Trial.International journal of environmental research and public health · 2023
    Trial
  2. Article
  3. Causal Mediation Analysis of FoodbornePathogens (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Causal mediation and sensitivity analysis for mixed-scale data.Statistical methods in medical research · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing Cheng1 Division of Oral Epidemiology & Dental Public Health, University of California at San Francisco, CA, USA.
Nancy F Cheng1 Division of Oral Epidemiology & Dental Public Health, University of California at San Francisco, CA, USA.
Zijian Guo2 Department of Statistics, Wharton School, University of Pennsylvania, PA, USA.
Steven Gregorich3 Department of Medicine, School of Medicine, University of California at San Francisco, CA, USA.
Amid I Ismail4 Department of Restorative Dentistry, Maurice H. Kornberg School of Dentistry, Temple University, PA, USA.
Stuart A Gansky1 Division of Oral Epidemiology & Dental Public Health, University of California at San Francisco, CA, USA.

Funding

Statistics and Data Coordinating CenterU54DE019285 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GANSKY, STUART A · 2008 to 2014
$24.9M
STUDY OF A NEW PAYMENT SYSTEM FOR MEDICAIDU54DE014261 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ISMAIL, AMID I. · 2001 to 2007
$9.3M
NIDCR NIH HHS U54 DE014261NIDCR NIH HHS U54 DE019285
6 · The paper itself

Abstract

Different conventional and causal approaches have been proposed for mediation analysis to better understand the mechanism of a treatment. Count and zero-inflated count data occur in biomedicine, economics, and social sciences. This paper considers mediation analysis for count and zero-inflated count data under the potential outcome framework with nonlinear models. When there are post-treatment confounders which are independent of, or affected by, the treatment, we first define the direct, indirect, and total effects of our interest and then discuss various conditions under which the effects of interest can be identified. Proofs are provided for the sensitivity analysis proposed in the paper. Simulation studies show that the methods work well. We apply the methods to the Detroit Dental Health Project's Motivational Interviewing DVD trial for the direct and indirect effects of motivational interviewing on count and zero-inflated count dental caries outcomes.

Indexed as

Motivational InterviewingOutcome Assessment, Health CareAlgorithmsChildChild, PreschoolDental CariesFemaleHumansMaleMichiganModels, StatisticalNonlinear DynamicsDirect effectindirect effectpost-treatment confoundersensitivity analysissequential ignorability

Identifiers

PMID28067122
PMCPMC5502001

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.