Evidence map›Paper›PMID 28066763›Full record

ArticleFrontiers in bioengineering and biotechnology2016

Optimization and Characterization of the Synthetic Secondary Chromosome synVicII in

Sonja J Messerschmidt, Daniel Schindler, Celine M Zumkeller, Franziska S Kemter, Nadine Schallopp, Torsten Waldminghaus

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Modular Assembly of Synthetic Secondary Chromosomes.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  4. Synthetic biology (Oxford, England) · 2024
    Article
  5. Article
  6. Article
  7. MoCloFlex: A Modular Yet Flexible Cloning System.Frontiers in bioengineering and biotechnology · 2019
    Article
  8. Article
  9. Functionality of Two Origins of Replication inFrontiers in microbiology · 2018
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sonja J MesserschmidtLOEWE Center for Synthetic Microbiology, SYNMIKRO, Philipps-Universität Marburg , Marburg , Germany.
Daniel SchindlerLOEWE Center for Synthetic Microbiology, SYNMIKRO, Philipps-Universität Marburg , Marburg , Germany.
Celine M ZumkellerLOEWE Center for Synthetic Microbiology, SYNMIKRO, Philipps-Universität Marburg , Marburg , Germany.
Franziska S KemterLOEWE Center for Synthetic Microbiology, SYNMIKRO, Philipps-Universität Marburg , Marburg , Germany.
Nadine SchalloppLOEWE Center for Synthetic Microbiology, SYNMIKRO, Philipps-Universität Marburg , Marburg , Germany.
Torsten WaldminghausLOEWE Center for Synthetic Microbiology, SYNMIKRO, Philipps-Universität Marburg , Marburg , Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Learning by building is one of the core ideas of synthetic biology research. Consequently, building synthetic chromosomes is the way to fully understand chromosome characteristics. The last years have seen exciting synthetic chromosome studies. We had previously introduced the synthetic secondary chromosome synVicII in

Indexed as

bacteriachromosome biologydirected evolutiongenetic engineeringreplicon integritysynthetic chromosomessynthetic genomesVibrio cholerae

Identifiers

PMID28066763
PMCPMC5179572

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.