Evidence map›Paper›PMID 28066447›Full record

ArticleFrontiers in immunology2016

Retinoic Acid Signaling in B Cells Is Required for the Generation of an Effective T-Independent Immune Response.

Ellen Marks, Carla Ortiz, Eirini Pantazi, Charlotte S Bailey, Graham M Lord, Thomas J Waldschmidt, Randolph J Noelle, Raul Elgueta

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Ellen MarksDepartment of Mucosal Immunology, Division of Transplantation Immunology & Mucosal Biology, Guy's Hospital, King's College London , London , UK.
Carla OrtizDepartment of Immune Regulation and Intervention, Division of Transplantation Immunology & Mucosal Biology, Guy's Hospital, King's College London , London , UK.
Eirini PantaziDepartment of Immune Regulation and Intervention, Division of Transplantation Immunology & Mucosal Biology, Guy's Hospital, King's College London , London , UK.
Charlotte S BaileyDepartment of Immune Regulation and Intervention, Division of Transplantation Immunology & Mucosal Biology, Guy's Hospital, King's College London , London , UK.
Graham M LordDepartment of Mucosal Immunology, Division of Transplantation Immunology & Mucosal Biology, Guy's Hospital, King's College London , London , UK.
Thomas J WaldschmidtInterdisciplinary Graduate Program in Immunology, Carver College of Medicine, The University of Iowa , Iowa City, IA , USA.
Randolph J NoelleDepartment of Immune Regulation and Intervention, Division of Transplantation Immunology & Mucosal Biology, Guy's Hospital, King's College London, London, UK; Department of Microbiology and Immunology of Dartmouth Medical School, Norris Cotton Cancer Center, Lebanon, NH, USA.
Raul ElguetaDepartment of Immune Regulation and Intervention, Division of Transplantation Immunology & Mucosal Biology, Guy's Hospital, King's College London , London , UK.
Guy's Hospital · GBKing's College London · GBDartmouth College · USImmune Regulation (United Kingdom) · GBUniversity of Iowa · US

Funding

Medical Research Council G0802068Medical Research Council MR/J006742/1
6 · The paper itself

Abstract

Retinoic acid (RA) plays an important role in the balance of inflammation and tolerance in T cells. Furthermore, it has been demonstrated that RA facilitates IgA isotype switching in B cells

Indexed as

B cellimmunoglobulinsmarginal zoneperitoneumretinoic acid

Identifiers

PMID28066447
PMCPMC5179524
OpenAlexW2562816548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.