Evidence map›Paper›PMID 28066430›Full record

ArticleFrontiers in immunology2016

Increase of Frequency and Modulation of Phenotype of Regulatory T Cells by Atorvastatin Is Associated with Decreased Lung Inflammatory Cell Infiltration in a Murine Model of Acute Allergic Asthma.

Yurany Blanquiceth, Ana Lucia Rodríguez-Perea, Jorge H Tabares Guevara, Luis Alfonso Correa, María Dulfary Sánchez, José Robinson Ramírez-Pineda, Paula Andrea Velilla

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Journal of asthma and allergy · 2021
    Article
  2. The potential of Atorvastatin for chronic lung diseases therapy.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020
    Review
  3. Mitochondrial DNA Leakage Caused byFrontiers in microbiology · 2019
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yurany BlanquicethGrupo Inmunovirología, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad de Antioquia UdeA , Medellín , Colombia.
Ana Lucia Rodríguez-PereaGrupo Inmunovirología, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad de Antioquia UdeA , Medellín , Colombia.
Jorge H Tabares GuevaraGrupo Inmunomodulación, Facultad de Medicina, Universidad de Antioquia UdeA , Medellín , Colombia.
Luis Alfonso CorreaSección de Dermatología, Departamento de Medicina, Facultad de Medicina, Universidad de Antioquia UdeA, Medellín, Colombia; Laboratorio de Patología, Laboratorio Clínico VID, Obra de la Congregación Mariana, Medellín, Colombia.
María Dulfary SánchezStanley S. Scott Cancer Center & Louisiana Cancer Research Center, Health Sciences Center, Louisiana State University , New Orleans, LA , USA.
José Robinson Ramírez-PinedaGrupo Inmunomodulación, Facultad de Medicina, Universidad de Antioquia UdeA , Medellín , Colombia.
Paula Andrea VelillaGrupo Inmunovirología, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad de Antioquia UdeA , Medellín , Colombia.
Universidad de Antioquia · COLouisiana State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory T cells (Tregs) play an important role by controlling allergic inflammation of airways. Recently, it has been shown that statins have immunomodulatory properties, probably mediated by their effects on Tregs. Therefore, we evaluated the

Indexed as

asthmaatorvastatinIL-10ovalbuminregulatory T cells

Identifiers

PMID28066430
PMCPMC5174085
OpenAlexW2561646319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.