Evidence map›Paper›PMID 28066417›Full record

ReviewFrontiers in immunology2016

Regulatory Functions of Natural Killer Cells in Multiple Sclerosis.

Catharina C Gross, Andreas Schulte-Mecklenbeck, Heinz Wiendl, Emanuela Marcenaro, Nicole Kerlero de Rosbo, Antonio Uccelli, Alice Laroni

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Natural Killer Cells: Dual Regulators and Therapeutic Targets in Multiple Sclerosis Immunopathogenesis.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. CNS Resident Innate Immune Cells: Guardians of CNS Homeostasis.International journal of molecular sciences · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Regulatory NK cells in autoimmune disease.Iranian journal of basic medical sciences · 2023
    Review
  15. Article
  16. Article
  17. Temporal Expression of Transcription FactorACS synthetic biology · 2022
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Catharina C GrossDepartment of Neurology, University Hospital Münster , Münster , Germany.
Andreas Schulte-MecklenbeckDepartment of Neurology, University Hospital Münster , Münster , Germany.
Heinz WiendlDepartment of Neurology, University Hospital Münster , Münster , Germany.
Emanuela MarcenaroCentre of Excellence for Biomedical Research, University of Genova, Genova, Italy; Department of Experimental Medicine, University of Genova, Genova, Italy.
Nicole Kerlero de RosboDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova , Genova , Italy.
Antonio UccelliCentre of Excellence for Biomedical Research, University of Genova, Genova, Italy; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy; IRCCS San Martino-IST, Genova, Italy.
Alice LaroniCentre of Excellence for Biomedical Research, University of Genova, Genova, Italy; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy; IRCCS San Martino-IST, Genova, Italy.
University of Genoa · ITUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is increasing evidence that natural killer (NK) cells exhibit regulatory features. Among them, CD56

Indexed as

CD56bright NK cellsCD56dim NK cellsinnate immune systemmultiple sclerosisnatural killer cellsregulatory immune cells

Identifiers

PMID28066417
PMCPMC5165263
OpenAlexW2565551410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.