Evidence map›Paper›PMID 28066411›Full record

ArticleFrontiers in immunology2016

Relation between Acute GVHD and NK Cell Subset Reconstitution Following Allogeneic Stem Cell Transplantation.

Evelyn Ullrich, Emilia Salzmann-Manrique, Shahrzad Bakhtiar, Melanie Bremm, Stephanie Gerstner, Eva Herrmann, Peter Bader, Petra Hoffmann, Ernst Holler, Matthias Edinger and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Low-dose IL-2 induces CD56Clinical and experimental immunology · 2020
    Article
  15. Review
  16. Article
  17. [Efficacy and peripheral immunity analysis of allogeneic natural killer cells therapy in patients with hepatocellular carcinoma].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2019
    Article
  18. Review
  19. Shaping of CD56Frontiers in immunology · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Evelyn UllrichLOEWE Center for Cell and Gene Therapy, Goethe University, Frankfurt, Germany; Division for Stem Cell Transplantation and Immunology, Department for Children and Adolescents Medicine, Hospital of the Goethe University Frankfurt, Frankfurt, Germany.
Emilia Salzmann-ManriqueDivision for Stem Cell Transplantation and Immunology, Department for Children and Adolescents Medicine, Hospital of the Goethe University Frankfurt , Frankfurt , Germany.
Shahrzad BakhtiarDivision for Stem Cell Transplantation and Immunology, Department for Children and Adolescents Medicine, Hospital of the Goethe University Frankfurt , Frankfurt , Germany.
Melanie BremmDivision for Stem Cell Transplantation and Immunology, Department for Children and Adolescents Medicine, Hospital of the Goethe University Frankfurt , Frankfurt , Germany.
Stephanie GerstnerLOEWE Center for Cell and Gene Therapy, Goethe University , Frankfurt , Germany.
Eva HerrmannInstitute of Biostatistics and Mathematical Modeling, Johann Wolfgang Goethe University , Frankfurt , Germany.
Peter BaderLOEWE Center for Cell and Gene Therapy, Goethe University, Frankfurt, Germany; Division for Stem Cell Transplantation and Immunology, Department for Children and Adolescents Medicine, Hospital of the Goethe University Frankfurt, Frankfurt, Germany.
Petra HoffmannDepartment of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany; Regensburg Center for Interventional Immunology (RCI), University of Regensburg, Regensburg, Germany.
Ernst HollerDepartment of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany; Regensburg Center for Interventional Immunology (RCI), University of Regensburg, Regensburg, Germany.
Matthias EdingerDepartment of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany; Regensburg Center for Interventional Immunology (RCI), University of Regensburg, Regensburg, Germany.
Daniel WolffDepartment of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany; Regensburg Center for Interventional Immunology (RCI), University of Regensburg, Regensburg, Germany.
Goethe University Frankfurt · DEUniversity Hospital Regensburg · DEUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the major challenges of allogeneic stem cell transplantation (allo-SCT) is to reduce the risk of graft-versus-host disease (GVHD) while boosting the graft-versus-leukemia (GVL) effect. The reconstitution of natural killer (NK) cells following allo-SCT is of notable interest due to their known capability to induce GVL without GVHD. Here, in this study, we investigate the association between the incidence and severity of acute graft-versus-host disease (aGVHD) and the early reconstitution of NK cell subsets following allo-SCT. We analyzed 342 samples from 107 patients using flow cytometry, with a focus on immature CD56

Indexed as

GVHDimmune reconstitutionNK cellNK cell subsetSCT

Identifiers

PMID28066411
PMCPMC5177660
OpenAlexW2565612372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.